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  1. Pneumocystis jiroveci pneumonia (PJP) is an opportunistic infection affecting immunocompromised individuals. However, evidence regarding the burden and effectiveness of prophylaxis among rheumatic patients remain...

    Authors: Shirley Chiu Wai Chan, Ho Yin Chung, Chak Sing Lau and Philip Hei Li

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:78

    Content type: Research

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  2. Escherichia coli is among the most common uropathogens. Increased antibiotic resistance in Gram negative bacilli is global concern. Alternative therapeutic options including vaccines against uropathogenic E. coli

    Authors: Miri Hyun, Ji Yeon Lee and Hyun ah Kim

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:77

    Content type: Research

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  3. The emergence of carbapenem-resistant Pseudomonas aeruginosa is one of the most important challenges in a healthcare setting. The aim of this study is double-locus sequence typing (DLST) typing of blaNDM-1 positi...

    Authors: Mojtaba Shahin and Ali Ahmadi

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:76

    Content type: Research

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  4. β-Lactam antibiotics have been broadly used for the treatment of Acinetobacter baumannii infections, resulting in development of β-lactam inactivating β-lactamases. Here, we described antibiotic resistance rate, ...

    Authors: Neda Yousefi Nojookambari, Mehrzad Sadredinamin, Razieh Dehbanipour, Zohreh Ghalavand, Gita Eslami, Maryam Vaezjalali, Bahram Nikmanesh and Sajjad Yazdansetad

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:75

    Content type: Research

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  5. Carbapenemase-producing Klebsiella pneumoniae (CP-KP) is becoming extensively disseminated in Iranian medical centers. Colistin is among the few agents that retains its activity against CP-KP. However, the admini...

    Authors: Negin Bolourchi, Fereshteh Shahcheraghi, Christian G. Giske, Shoeib Nematzadeh, Narjes Noori Goodarzi, Hamid Solgi and Farzad Badmasti

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:74

    Content type: Research

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  6. Mycobacterium tuberculosis (MTB) is responsible for tuberculosis; that continues to be a public health threat across the globe. Furthermore, increasing heteroresistance (HR)-the presence of resistant and suscepti...

    Authors: Mao Ye, Wen Yuan, Leila Molaeipour, Khalil Azizian, Alireza Ahmadi and Ebrahim Kouhsari

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:73

    Content type: Review

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  7. Francisella philomiragia is a very rare opportunistic pathogen of humans which causes protean diseases such as pneumonia and other systemic infections. Subsequent failure of prompt treatment may result in poor pr...

    Authors: Hui Shan Chua, Yih Harng Soh, Shih Keng Loong and Sazaly AbuBakar

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:72

    Content type: Case report

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  8. Corynebacterium striatum was confirmed to be an important opportunistic pathogen, which could lead to multiple-site infections and presented high prevalence of multidrug resistance, particularly to quinolone anti...

    Authors: Yingjun Wang, Xiaohong Shi, Jian Zhang, Yanyan Wang, Yingying Lv, Xiaoli Du, QiQiGe ChaoLuMen and Junrui Wang

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:71

    Content type: Research

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  9. Klebsiella pneumoniae is one of the leading causes of hospital outbreaks worldwide. Also, antibiotic-resistant K. pneumoniae is progressively being involved in invasive infections with high morbidity and mortalit...

    Authors: Mojgan Farhadi, Mohammad Ahanjan, Hamid Reza Goli, Mohammad Reza Haghshenas and Mehrdad Gholami

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:70

    Content type: Research

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  10. Coronavirus SARS-CoV-2 causes COVID-19 illness which can progress to severe pneumonia. Empiric antibacterials are often employed though frequency of bacterial coinfection superinfection is debated and concerns...

    Authors: Hans H. Liu, David Yaron, Amanda Stahl Piraino and Luciano Kapelusznik

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:69

    Content type: Research

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  11. Staphylococcus schleiferi is a gram-positive pathogenic coccus which causes canine skin and ear infections. Only four cases of human infection caused by Staphylococcus schleiferi subspecies coagulans have been re...

    Authors: Tatsuya Kobayashi, Mahoko Ikeda, Yuki Ohama, Koji Murono, Kazuhiko Ikeuchi, Satoshi Kitaura, Koh Okamoto, Shu Okugawa, Soichiro Ishihara and Kyoji Moriya

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:68

    Content type: Case report

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  12. Methicillin-resistance S. aureus (MRSA) possesses the ability to resist multiple antibiotics and form biofilm. Currently, vancomycin remains the last drug of choice for treatment of MRSA infection. The emergence ...

    Authors: Pooi Yin Chung, Ranon Earn Yueh Khoo, Hui Shan Liew and May Lee Low

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:67

    Content type: Research

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  13. To date, there is no specific antiviral therapy for severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) that causes Coronavirus disease 2019 (Covid-19). Since there is no specific therapy against SARS...

    Authors: Miguel Alejandro Pinzón, Doris Cardona Arango, Juan Felipe Betancur, Santiago Ortiz, Héctor Holguín, Carolina Arias Arias, Bernardo J. Muñoz Palacio, Michael Amarillo, Juan Felipe Llano and Pablo Montoya

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:66

    Content type: Research

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  14. This study aimed to investigate the phylogenetic characterization and virulence traits of uropathogenic Escherichia coli (UPEC) isolated from kidney transplant patients (KTPs) as well as non-KTPs and analyze the ...

    Authors: Mehrdad Halaji, Shahrzad Shahidi, Behrooz Ataei, Abdolamir Atapour, Awat Feizi and Seyed Asghar Havaei

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:65

    Content type: Research

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  15. Bacterial superinfections associated with COVID-19 are common in ventilated ICU patients and impact morbidity and lethality. However, the contribution of antimicrobial resistance to the manifestation of bacter...

    Authors: Marina Gysin, Claudio Tirso Acevedo, Klara Haldimann, Elias Bodendoerfer, Frank Imkamp, Karl Bulut, Philipp Karl Buehler, Silvio Daniel Brugger, Katja Becker and Sven N. Hobbie

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:64

    Content type: Research

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  16. Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae has become a public health concern. This study aimed to compare the clinical outcomes of patients with nonurinary source bacteraemia caused by ...

    Authors: Hong Luo, Yanping Xiao, Yaping Hang, Yanhui Chen, Hongying Zhu, Xueyao Fang, Xingwei Cao, Shan Zou, Xiaoyan Hu, Jianqiu Xiong, Qiaoshi Zhong and Longhua Hu

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:63

    Content type: Research

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  17. Group B Streptococcal (GBS) infection is the primary agent of neonatal morbidity and mortality. Rapid and simple methods to detect GBS are Xpert GBS and GBS LB assays based on real-time polymerase chain reaction ...

    Authors: Meng-Yi Han, Chen Xie, Qing-Qing Huang, Qiao-Hua Wu, Qing-Yun Deng, Tian-Ao Xie, Ye-Ling Liu, Zhuo-Lei Li, Jing-Hua Zhong, Yan-Chao Wang and Xu-Guang Guo

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:62

    Content type: Research

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  18. It is essential to detect carriers of carbapenemase-producing Enterobacterales in order to implement infection control measures. The objectives of this study was to evaluate the NG-Test® CARBA 5 (CARBA 5) assay f...

    Authors: Hadas Kon, Shirin Abramov, Sammy Frenk, David Schwartz, Ohad Shalom, Amos Adler, Yehuda Carmeli and Jonathan Lellouche

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:61

    Content type: Research

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  19. Blood stream infections (BSI) caused by Extended Spectrum Beta-Lactamases (ESBLs) producing Enterobacteriaceae is a clinical challenge leading to high mortality, especially in developing countries. In this study,...

    Authors: Trinh Van Son, Nguyen Dang Manh, Ngo Tat Trung, Dao Thanh Quyen, Christian G. Meyer, Nguyen Thi Kim Phuong, Phan Quoc Hoan, Vu Viet Sang, Dennis Nurjadi, Thirumalaisamy P. Velavan, Mai Hong Bang and Le Huu Song

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:60

    Content type: Research

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  20. Chlamydiae are intracellular bacteria that cause various severe diseases in humans and animals. The common treatment for chlamydia infections are antibiotics. However, when antibiotics are misused (overuse or ...

    Authors: Ichrak Benamri, Maryame Azzouzi, Kholoud Sanak, Ahmed Moussa and Fouzia Radouani

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:59

    Content type: Review

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  21. Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a pathogen of global concern. In this study, both phenotypic and genotypic tests were used to detect hvKp. Antimicrobial resistance profiles and clonal re...

    Authors: Rahimeh Sanikhani, Mohammad Moeinirad, Hamid Solgi, Azar Hadadi, Fereshteh Shahcheraghi and Farzad Badmasti

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:58

    Content type: Research

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  22. Carbapenem-resistant Enterobacteriaceae are a worldwide health problem and isolates carrying both blaKPC-2 and blaNDM-1 are unusual. Here we describe the microbiological and clinical characteristics of five cases...

    Authors: Taniela Bes, Debora Nagano, Roberta Martins, Ana Paula Marchi, Lauro Perdigão-Neto, Hermes Higashino, Gladys Prado, Thais Guimaraes, Anna S. Levin and Silvia Costa

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:57

    Content type: Short report

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  23. According to World Health Organization (WHO), drug-resistant tuberculosis (DR-TB) is a major contributor to antimicrobial resistance globally and continues to be a public health threat. Annually, about half a ...

    Authors: Kamal Singh, Richa Kumari, Smita Gupta, Rajneesh Tripathi, Anjali Srivastava, Vidisha Shakya, Ankush Gupta and Shampa Anupurba

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:56

    Content type: Research

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  24. To explore disease severity and risk factors for 30-day mortality of adult immunocompromised (IC) patients hospitalized with influenza-related pneumonia (Flu-p).

    Authors: Liang Chen, Xiudi Han, YanLi Li, Chunxiao Zhang and Xiqian Xing

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:55

    Content type: Research

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  25. Multidrug resistant (MDR) and biofilm producing Staphylococcus aureus strains are usually associated with serious infections. This study aimed to evaluate the antibacterial and antibiofilm-formation effects of zi...

    Authors: Wedad M. Abdelraheem, Rasha M. M. Khairy, Alaa I. Zaki and Shaimaa H. Zaki

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:54

    Content type: Research

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  26. Although pertussis cases globally have been controlled through the Expanded Programme on Immunization (EPI), the incidence of pertussis has increased significantly in recent years, with a “resurgence” of pertu...

    Authors: Shuang Wu, Qinghua Hu, Chao Yang, Haijian Zhou, Hongyu Chen, Yanwei Zhang, Min Jiang, Yuxiang He and Xiaolu Shi

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:53

    Content type: Research

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  27. The resistance of Neisseria gonorrhoeae to ceftriaxone is unusual in Switzerland. The underlying genotype responsible for resistance is suspected to be novel. Generally, resistance in Neisseria gonorrhoeae (Ng) i...

    Authors: Konrad Egli, Anna Roditscheff, Ursula Flückiger, Martin Risch, Lorenz Risch and Thomas Bodmer

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:52

    Content type: Case report

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  28. In this study, we aimed to evaluate the epidemiology and antimicrobial resistance (AMR) patterns of bacterial pathogens in COVID-19 patients and to compare the results with control groups from the pre-pandemic...

    Authors: Mustafa Karataş, Melike Yaşar-Duman, Alper Tünger, Feriha Çilli, Şöhret Aydemir and Volkan Özenci

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:51

    Content type: Research

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  29. Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract infection (UTI); however, treatment of UTI has been challenging due to increased antimicrobial resistance (AMR). One of the most important t...

    Authors: Fatemeh Zangane Matin, Seyedeh Elham Rezatofighi, Mohammad Roayaei Ardakani, Mohammad Reza Akhoond and Fahimeh Mahmoodi

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:50

    Content type: Research

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  30. Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas systems are one of the factors which can contribute to limiting the development and evolution of antibiotic resistance in bacteria. There a...

    Authors: Pourya Gholizadeh, Mohammad Aghazadeh, Reza Ghotaslou, Mohammad Ahangarzadeh Rezaee, Tahereh Pirzadeh, Longzhu Cui, Shinya Watanabe, Hadi Feizi, Hiva Kadkhoda and Hossein Samadi Kafil

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:49

    Content type: Research

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  31. Commensal flora colonization during hospitalization by bacteria is the first step for nosocomial infections while antibiotic resistance reduces therapeutic options. In aim to control this phenomenon, we initia...

    Authors: William Lelorel Nguekap Nankam, Pierre René Fotsing Kwetche, Gildas Boris Tazemda-Kuitsouc, Golda Joyce Djeutsa Chouna and Jean Michel Tekam

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:48

    Content type: Research

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  32. Pneumocystis jirovecii and Aspergillus fumigatus, are opportunistic pathogenic fungus that has a major impact on mortality in patients with systemic lupus erythematosus. With the potential to invade multiple orga...

    Authors: Yili Chen, Lu Ai, Yingqun Zhou, Yating Zhao, Jianyu Huang, Wen Tang and Yujian Liang

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:47

    Content type: Case report

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  33. This case report describes a neck abscess caused by a strain of Hypervirulent Klebsiella pneumoniae in a middle aged man with diabetes without a history of travel to East and South East Asia. This case report is ...

    Authors: John Alexander McHardy, Vathshalan Selvaganeshapillai, Priya Khanna, Ashley Michael Whittington, Jane Turton and Guduru Gopal Rao

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:46

    Content type: Case report

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  34. A complex cascade of genes, enzymes, and transcription factors regulates AmpC β-lactamase overexpression. We investigated the network of AmpC β-lactamase overexpression in Klebsiella aerogenes and identified the ...

    Authors: Roshan D’Souza, Le Phuong Nguyen, Naina A. Pinto, Hyunsook Lee, Thao Nguyen Vu, Hoyoung Kim, Hyun Soo Cho and Dongeun Yong

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:45

    Content type: Research

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  35. Aspergillosis of Central Nervous System (CNS) is a highly lethal infection in patients with leukemia and Stem Cell Transplantation (SCT).

    Authors: Aref Shariati, Mojtaba Didehdar, Shahin Rajaeih, Alireza Moradabadi, Mohammad Ghorbani, Vahid Falahati and Zahra Chegini

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:44

    Content type: Review

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  36. Studying time-related changes in susceptible pathogens causing healthcare-associated infections (HAIs) is vital in improving local antimicrobial and infection control practices.

    Authors: Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Ahmad J. Alzahrani, Mansour Tobaiqy, Ahmed M. Alresasi, Ibrahim Bu-Shehab, Issa Al-Hadary, Naif Alhmeed, Mossa Alismail, Ahmed H. Aldera, Fadhil AlHbabi, Haifa Al-Shammari, Ali A. Rabaan and Awad Al-Omari

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:43

    Content type: Research

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  37. Correctly identifying anaerobic bloodstream infections (BSIs) is difficult. However, a new technique, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), enables more a...

    Authors: Tsuyoshi Watanabe, Yuki Hara, Yusuke Yoshimi, Waka Yokoyama-kokuryo, Yoshiro Fujita, Masamichi Yokoe and Yoshinori Noguchi

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:42

    Content type: Research

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  38. Coagulase-negative staphylococci (CNS) survive as commensals of skin, anterior nares and external canals of human and were regarded as non-infectious pathogens. However, they are emerging as a major cause of n...

    Authors: Sarita Manandhar, Anjana Singh, Ajit Varma, Shanti Pandey and Neeraj Shrivastava

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:41

    Content type: Research

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  39. Treatment of burn wound infections has become a global challenge due to the spread of multidrug-resistant bacteria; therefore, the development of new treatment options for the mentioned infections is essential...

    Authors: Aref Shariati, Alireza Moradabadi, Ehsanollah Ghaznavi-Rad, Maryam Dadmanesh, Majid Komijani and Farshad Nojoomi

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:40

    Content type: Research

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  40. There is limited and controverting evidence looking at possible associations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA copies and patient variables in large cohorts of symptomatic and...

    Authors: Santiago A. Quiroga, Carolina Hernández, Sergio Castañeda, Paula Jimenez, Laura Vega, Marcela Gomez, David Martinez, Nathalia Ballesteros, Marina Muñoz, Claudia Cifuentes, Nathalia Sierra, Carolina Flórez, Alberto Paniz-Mondolfi and Juan David Ramírez

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:39

    Content type: Research

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  41. SARS-CoV-2 is a newly emerged coronavirus, causing the coronavirus disease 2019 (COVID-19) outbreak in December, 2019. As drugs and vaccines of COVID-19 remain in development, accurate virus detection plays a ...

    Authors: Shuang Wu, Xiaolu Shi, Qiongcheng Chen, Yixiang Jiang, Le Zuo, Lei Wang, Min Jiang, Yiman Lin, Shisong Fang, Bo Peng, Weihua Wu, Hui Liu, Renli Zhang, Patrick S. L. Kwan and Qinghua Hu

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:38

    Content type: Research

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  42. Drug repurposing otherwise known as drug repositioning or drug re-profiling is a time-tested approach in drug discovery through which new medical uses are being established for already known drugs. Antibiotics...

    Authors: Abdourahamane Yacouba, Ahmed Olowo-okere and Ismaeel Yunusa

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:37

    Content type: Review

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  43. Campylobacter resistance to antimicrobial agents is regarded as a major concern worldwide. The aim of this study was to investigate the expression of the CmeABC efflux pump and the RAPD-PCR pattern in drug-resist...

    Authors: Saeed Sharifi, Bita Bakhshi and Shahin Najar-peerayeh

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:36

    Content type: Research

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  44. Coronavirus disease 2019 (COVID-19) is the second pandemic of the twenty-first century, with over one-hundred million infections and over two million deaths to date. It is a novel strain from the Coronaviridae fa...

    Authors: Saad I. Mallah, Omar K. Ghorab, Sabrina Al-Salmi, Omar S. Abdellatif, Tharmegan Tharmaratnam, Mina Amin Iskandar, Jessica Atef Nassef Sefen, Pardeep Sidhu, Bassam Atallah, Rania El-Lababidi and Manaf Al-Qahtani

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:35

    Content type: Review

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  45. The incidence of Candida bloodstream infections (BSIs), has increased over time. In this study, we aimed to describe the current epidemiology of Candida BSI in a large tertiary care hospital in Shanghai and to de...

    Authors: Yan-Jun Zheng, Ting Xie, Lin Wu, Xiao-Ying Liu, Ling Zhu, Ying Chen, En-Qiang Mao, Li-Zhong Han, Er-Zhen Chen and Zhi-Tao Yang

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:34

    Content type: Research

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  46. Globally, surgical site infections are the most reported healthcare-associated infection and common surgical complication. In developing countries such as Ethiopia, there is a paucity of published reports on t...

    Authors: Gemedo Misha, Legese Chelkeba and Tsegaye Melaku

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:33

    Content type: Research

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  47. We evaluated the distribution of carbapenem and colistin resistance mechanisms of clinical E. coli and K. pneumoniae isolates from Iran.

    Authors: Javad Yasbolaghi Sharahi, Ali Hashemi, Abdollah Ardebili and Sara Davoudabadi

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:32

    Content type: Research

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  48. This study aimed to investigate the specific risk factors for the transmission of novel coronavirus (SARS-CoV-2) among healthcare workers in different campuses of a university hospital and to reveal the risk f...

    Authors: Aziz Ogutlu, Oguz Karabay, Unal Erkorkmaz, Ertugrul Guclu, Seher Sen, Abdulkadir Aydin and Mehmet Koroglu

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:31

    Content type: Research

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  49. Multi-Drug Resistant (MDR) uropathogenic bacteria have increased in number in recent years and the development of new treatment options for the corresponding infections has become a major challenge in the fiel...

    Authors: Zahra Chegini, Amin Khoshbayan, Soheil Vesal, Alireza Moradabadi, Ali Hashemi and Aref Shariati

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:30

    Content type: Review

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  50. Resistance, prolonged therapy, and more adverse reactions made amoxicillin less preferred for treating otitis media. This study aimed to compare the efficacy and safety of azithromycin and amoxicillin/clavulan...

    Authors: Gabriel Dawit, Solomon Mequanent and Eyasu Makonnen

    Citation: Annals of Clinical Microbiology and Antimicrobials 2021 20:28

    Content type: Research

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