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  1. Research

    PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis

    The Mycobacterium tuberculosis (M.tb) protein kinase B (PknB) which is now proved to be essential for the growth and survival of M.tb, is a transmembrane protein with a potential to be a good drug target. However...

    Anamika Gupta, Sudhir K. Pal, Divya Pandey, Najneen A. Fakir, Sunita Rathod, Dhiraj Sinha, S. SivaKumar, Pallavi Sinha, Mycal Periera, Shilpa Balgam, Gomathi Sekar, K. R. UmaDevi, Shampa Anupurba and Vijay Nema

    Annals of Clinical Microbiology and Antimicrobials 2017 16:56

    Published on: 18 August 2017

  2. Research

    Molecular determination of antimicrobial resistance in Escherichia coli isolated from raw meat in Addis Ababa and Bishoftu, Ethiopia

    Consumption of meat contaminated by E. coli causes a serious illness and even death to affected individuals. Recently the emerging of antibiotic resistant foodborne E. coli poses serious public health risks world...

    Yohannes Equar Messele, Reta Duguma Abdi, Shimels Tikuye Yalew, Desiye Tesfaye Tegegne, Bezina Arega Emeru and Gebremeskel Mamu Werid

    Annals of Clinical Microbiology and Antimicrobials 2017 16:55

    Published on: 15 August 2017

  3. Case report

    Second-line therapy for Helicobacter pylori eradication causing antibiotic-associated hemorrhagic colitis

    Helicobacter pylori (H. pylori) eradication rarely develops into antibiotic-associated hemorrhagic colitis (AAHC), in which the etiology of colitis remains unclear. We herein report a ...

    Kazuyuki Tanaka, Mikihiro Fujiya, Aki Sakatani, Shugo Fujibayashi, Yoshiki Nomura, Nobuhiro Ueno, Shin Kashima, Takuma Goto, Junpei Sasajima, Kentaro Moriichi and Toshikatsu Okumura

    Annals of Clinical Microbiology and Antimicrobials 2017 16:54

    Published on: 14 August 2017

  4. Research

    An assessment on the role of endophytic microbes in the therapeutic potential of Fagonia indica

    Natural products of animals, plants and microbes are potential source of important chemical compounds, with diverse applications including therapeutics. Endophytic bacteria that are especially associated with ...

    Lubna Rahman, Zabta K. Shinwari, Irum Iqrar, Lutfur Rahman and Faouzia Tanveer

    Annals of Clinical Microbiology and Antimicrobials 2017 16:53

    Published on: 1 August 2017

  5. Research

    Influence of borderline cefepime MIC on the outcome of cefepime-susceptible Pseudomonas aeruginosa bacteremia treated with a maximal cefepime dose: a hospital-based retrospective study

    We assessed the influence of current cefepime minimal inhibitory concentration (MIC) breakpoints and the maximal cefepime dose on treatment outcomes in patients with bacteremia caused by cefepime-susceptible Pseu...

    Ting-Yi Su, Jung-Jr Ye, Chien-Chang Yang, Ching-Tai Huang, Ju-Hsin Chia and Ming-Hsun Lee

    Annals of Clinical Microbiology and Antimicrobials 2017 16:52

    Published on: 24 July 2017

  6. Research

    Molecular characterization and genetic relatedness of clinically Acinetobacter baumanii isolates conferring increased resistance to the first and second generations of tetracyclines in Iran

    The increasing resistance of Acinetobacter baumannii to antibiotics has recently been regarded as a notable therapeutic difficulty. Evaluating resistance rates of some A. baumannii isolates to tetracyclines had a...

    Zahra Meshkat, Himen Salimizand, Yousef Amini, Mostafa Khakshoor, Davoud Mansouri, Hadi Farsiani, Kiarash Ghazvini and Adel Najafi

    Annals of Clinical Microbiology and Antimicrobials 2017 16:51

    Published on: 19 July 2017

  7. Research

    Antimicrobial susceptibility among Gram-positive and Gram-negative organisms collected from the Latin American region between 2004 and 2015 as part of the Tigecycline Evaluation and Surveillance Trial

    The in vitro activity of tigecycline and comparator agents was evaluated against Gram-positive and Gram-negative isolates collected in Latin American centers between 2004 and 2015 as part of the Tigecycline Ev...

    Silvio Vega and Michael J. Dowzicky

    Annals of Clinical Microbiology and Antimicrobials 2017 16:50

    Published on: 12 July 2017

  8. Research

    Prevalence of multi drug resistant enteropathogenic and enteroinvasive Escherichia coli isolated from children with and without diarrhea in Northeast Indian population

    Diarrheagenic Escherichia coli are associated with infantile diarrhea in the developing countries. The present study was conducted to determine the occurrence and antimicrobial resistance pattern of enteropathoge...

    Karuppasamy Chellapandi, Tapan Kumar Dutta, Indu Sharma, Surajit De Mandal, Nachimuthu Senthil Kumar and Lalsanglura Ralte

    Annals of Clinical Microbiology and Antimicrobials 2017 16:49

    Published on: 11 July 2017

  9. Research

    Comparison of in-house and commercial real time-PCR based carbapenemase gene detection methods in Enterobacteriaceae and non-fermenting gram-negative bacterial isolates

    Carbapenemase-producing gram-negative bacteria are increasing globally and have been associated with outbreaks in hospital settings. Thus, the accurate detection of these bacteria in infections is mandatory fo...

    M. Smiljanic, M. Kaase, P. Ahmad-Nejad and B. Ghebremedhin

    Annals of Clinical Microbiology and Antimicrobials 2017 16:48

    Published on: 10 July 2017

  10. Research

    Parasitological and biochemical studies on cutaneous leishmaniasis in Shara’b District, Taiz, Yemen

    The leishmaniasis is a group of diseases caused by intracellular haemoflagellate protozoan parasites of the genus Leishmania. Leishmaniasis has diverse clinical manifestations; cutaneous leishmaniasis (CL) is the...

    Qhtan Asmaa, Salwa AL-Shamerii, Mohammed Al-Tag, Adam AL-Shamerii, Yiping Li and Bashir H. Osman

    Annals of Clinical Microbiology and Antimicrobials 2017 16:47

    Published on: 4 July 2017

  11. Research

    Profiling of antibiotic resistance of bacterial species recovered from routine clinical isolates in Ethiopia

    With the alarming rise in antibiotic resistance in African countries, the need for a surveillance system in the region has become pressing. The rapid expansion of data networks makes it possible to set up heal...

    Robert-Jan ten Hove, Melaku Tesfaye, Witold Frederik ten Hove and Mesfin Nigussie

    Annals of Clinical Microbiology and Antimicrobials 2017 16:46

    Published on: 26 June 2017

  12. Research

    Prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium and Ureaplasma urealyticum infections using a novel isothermal simultaneous RNA amplification testing method in infertile males

    The purpose of this study was to evaluate the prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium and Ureaplasma urealyticum infections in infertile men that consulted our outpatient...

    Ling Qing, Qi-Xiang Song, Jian-Li Feng, Hai-Yan Li, Guiming Liu and Hai-Hong Jiang

    Annals of Clinical Microbiology and Antimicrobials 2017 16:45

    Published on: 24 June 2017

  13. Case report

    Tuberculosis arthritis of the sternoclavicular joint after uncomplicated falciparum malaria: a case report

    Malaria and tuberculosis are co-endemic in many developing countries. However their associations are rarely reported. Yet, it has been suggested that a pathological process may link the two diseases.

    Boundia Djiba, Baidy Sy Kane, Mamadou Alpha Diallo, Khadim Diongue, Ngoné Diaba Diack, Hamidou Deme, Mouhamed Dieng, Maimouna Sow, Daouda Ndiaye and Abdoulaye Pouye

    Annals of Clinical Microbiology and Antimicrobials 2017 16:44

    Published on: 5 June 2017

  14. Research

    Effect of the 2014 Clinical and Laboratory Standards Institute urine-specific breakpoints on cefazolin susceptibility rates at a community teaching hospital

    Enterobacteriaceae, which include Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis, are identified as the infectious etiology in the majority of urinary tract infections (UTIs) in community hospital...

    Daniel B. Chastain, Ijang Ngando, Christopher M. Bland, Carlos Franco-Paredes and W. Anthony Hawkins

    Annals of Clinical Microbiology and Antimicrobials 2017 16:43

    Published on: 30 May 2017

  15. Research

    A pre-therapeutic coating for medical devices that prevents the attachment of Candida albicans

    Hospital acquired fungal infections are defined as “never events”—medical errors that should never have happened. Systemic Candida albicans infections results in 30–50% mortality rates. Typically, adhesion to abi...

    Diego Vargas-Blanco, Aung Lynn, Jonah Rosch, Rony Noreldin, Anthony Salerni, Christopher Lambert and Reeta P. Rao

    Annals of Clinical Microbiology and Antimicrobials 2017 16:41

    Published on: 19 May 2017

  16. Research

    Patients with community-acquired bacteremia of unknown origin: clinical characteristics and usefulness of microbiological results for therapeutic issues: a single-center cohort study

    Bacteremia of unknown origin (BUO) are associated with increased mortality compared to those with identified sources. Microbiological data of those patients could help to characterize an appropriate empirical ...

    Johan Courjon, Elisa Demonchy, Nicolas Degand, Karine Risso, Raymond Ruimy and Pierre-Marie Roger

    Annals of Clinical Microbiology and Antimicrobials 2017 16:40

    Published on: 19 May 2017

  17. Research

    Enzyme-mediated formulation of stable elliptical silver nanoparticles tested against clinical pathogens and MDR bacteria and development of antimicrobial surgical thread

    Silver nanoparticles (AgNPs) are believed to be emerging tool against various infectious diseases including multi-drug resistant (MDR) bacteria. In the present study, in vitro synthesis of AgNPs was optimized ...

    Rupak Thapa, Chintan Bhagat, Pragya Shrestha, Suvash Awal and Pravin Dudhagara

    Annals of Clinical Microbiology and Antimicrobials 2017 16:39

    Published on: 16 May 2017

  18. Research

    Determinants of felt demand for dengue vaccines in the North Caribbean region of Colombia

    The increasing burden associated with dengue in Latin America makes it essential to understand the community’s interest in acquiring vaccines, as an input to plan its introduction in endemic regions. The objec...

    Yalil T. Bracho-Churio, Ruth A. Martínez-Vega, Alfonso J. Rodriguez-Morales, Ronald G. Díaz-Quijano, María L. Luna-González and Fredi A. Diaz-Quijano

    Annals of Clinical Microbiology and Antimicrobials 2017 16:38

    Published on: 15 May 2017

  19. Short report

    Genome sequence of Shigella flexneri strain SP1, a diarrheal isolate that encodes an extended-spectrum β-lactamase (ESBL)

    Shigellosis is the most common cause of gastrointestinal infections in developing countries. In China, the species most frequently responsible for shigellosis is Shigella flexneri. S. flexneri remains largely une...

    Ping Shen, Jianzhong Fan, Lihua Guo, Jiahua Li, Ang Li, Jing Zhang, Chaoqun Ying, Jinru Ji, Hao Xu, Beiwen Zheng and Yonghong Xiao

    Annals of Clinical Microbiology and Antimicrobials 2017 16:37

    Published on: 12 May 2017

  20. Research

    Vitamin D deficiency among smear positive pulmonary tuberculosis patients and their tuberculosis negative household contacts in Northwest Ethiopia: a case–control study

    Vitamin D is a fat-soluble vitamin that increases the immunity against tuberculosis (TB), decreases the re-activation of latent TB and reduces the severity of active TB disease. Epidemiological studies on the ...

    Belay Tessema, Feleke Moges, Dereje Habte, Nebiyu Hiruy, Shewaye Yismaw, Kassahun Melkieneh, Yewulsew Kassie, Belaineh Girma, Muluken Melese and Pedro G. Suarez

    Annals of Clinical Microbiology and Antimicrobials 2017 16:36

    Published on: 11 May 2017

  21. Research

    Antimicrobial resistance and virulence characterization of Staphylococcus aureus and coagulase-negative staphylococci from imported beef meat

    The objectives of this study were to characterize the diversity and magnitude of antimicrobial resistance among Staphylococcus species recovered from imported beef meat sold in the Egyptian market and the potenti...

    Kamelia Osman, Avelino Alvarez-Ordóñez, Lorena Ruiz, Jihan Badr, Fatma ElHofy, Khalid S. Al-Maary, Ihab M. I. Moussa, Ashgan M. Hessain, Ahmed Orabi, Alaa Saad and Mohamed Elhadidy

    Annals of Clinical Microbiology and Antimicrobials 2017 16:35

    Published on: 10 May 2017

  22. Research

    The emergence of a novel sequence type of MDR Acinetobacter baumannii from the intensive care unit of an Egyptian tertiary care hospital

    Acinetobacter baumannii is known for nosocomial outbreaks worldwide. In this study, we aimed to investigate the antibiotic susceptibility patterns and the clonal relationship of A. bau...

    Doaa Mohammad Ghaith, Mai Mahmoud Zafer, Mohamed Hamed Al-Agamy, Essam J. Alyamani, Rayan Y. Booq and Omar Almoazzamy

    Annals of Clinical Microbiology and Antimicrobials 2017 16:34

    Published on: 10 May 2017

  23. Research

    Detection of a CTX-M group 2 beta-lactamase gene in a Klebsiella pneumoniae isolate from a tertiary care hospital, Trinidad and Tobago

    Identification of the prevalence and spread of ESBL-mediated antibiotic resistance is essential especially in the hospital setting. It is for this reason, more and more studies are highlighting the importance ...

    Paul Cheddie, Francis Dziva and Patrick Eberechi Akpaka

    Annals of Clinical Microbiology and Antimicrobials 2017 16:33

    Published on: 8 May 2017

  24. Research

    Molecular characteristic of mcr-1 producing Escherichia coli in a Chinese university hospital

    Colistin has been considered as a last-line treatment option in severe infections caused by multidrug-resistant (MDR) gram-negative pathogens. However, the emergence of the mobile colistin resistance gene (mcr-1)...

    Qing-wen He, Xiao-hong Xu, Fang-jun Lan, Zhi-chang Zhao, Zhi-yun Wu, Ying-ping Cao and Bin Li

    Annals of Clinical Microbiology and Antimicrobials 2017 16:32

    Published on: 19 April 2017

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