Table 5 Univariate and multivariate analysis of 3-year mortality

Control group

Ref.

Ref.

Ref.

MDR group

2.697 (2.357-3.085)

<0.001

1.900 (1.645-2.193)

<0.001

Control group

Ref.

Ref.

 MDR conversion

2.711 (2.316-3.172)

<0.001

1.850 (1.566-2.186)

<0.001

 MDR non-conversion

2.677 (2.241-3.198)

<0.001

1.971 (1.640-2.367)

<0.001

Age

1.039 (1.032-1.045)

<0.001

1.036 (1.029-1.043)

<0.001

1.036 (1.029-1.043)

<0.001

Sex (Female)

0.695 (0.605-0.799)

<0.001

0.745 (0.647-0.858)

<0.001

0.746 (0.648-0.858)

<0.001

BMI

0.934 (0.917-0.951)

<0.001

0.950 (0.933-0.967)

<0.001

0.950 (0.933-0.967)

<0.001

Previous exacerbation*

1.010 (1.004-1.016)

0.002

1.003 (0.995-1.102)

0.464

1.003 (0.995-1.012)

0.469

BACI index

1.036 (1.026-1.045)

<0.001

1.019 (1.009-1.030)

0.001

1.019 (1.009-1.030)

0.001

Acute kidney injury

2.329 (1.997-2.716)

<0.001

1.789 (1.526-2.098)

<0.001

1.793 (1.529-2.103)

<0.001

Hemodialysis

2.025 (1.583-2.590)

<0.001

1.593 (1.217-2.084)

0.001

1.602 (1.224-2.098)

0.001

Inhospital medication

 Systemic steroid

2.200 (1.914-2.529)

<0.001

1.643 (1.413-1.910)

<0.001

1.645 (1.415-1.913)

<0.001

 Inhalation steroid

1.327 (1.115-1.579)

0.001

0.998 (0.834-1.194)

0.979

0.999 (0.835-1.195)

0.989

 Antibiotic

3.707 (2.778-4.946)

<0.001

1.862 (1.376-2.519)

<0.001

1.859 (1.374-2.515)

<0.001