Table 3 Univariable analysis for factors associated with lung injury in delta variant–infected patients
POI in the whole lung, % | VOI in the whole lung, cm3 | The chest CT scores | ||||
|---|---|---|---|---|---|---|
Coefficient | P-value | Coefficient | P-value | Coefficient | P-value | |
Male (vs female) | − 0.87 (− 2.70,0.95) | 0.348 | 43.30 (− 10.29,96.89) | 0.114 | − 0.48 (− 1.33,0.38) | 0.275 |
Age ≥ 60 yeas (vs < 60 years) | 8.00 (6.25,9.76) | < 0.001 | 228.00 (175.88,280.20) | < 0.001 | 4.18 (3.38,4.98) | < 0.001 |
Comorbidity (vs. No) | 4.05 (2.11,5.98) | < 0.001 | 109.12 (51.80,166.44) | < 0.001 | 2.12 (1.22,3.02) | < 0.001 |
Vaccination status | ||||||
Unvaccinated | 1 | 1 | 1 | |||
Partially vaccinated | − 1.17 (− 3.58,1.24) | 0.341 | − 9.74 (− 80.56,61.08) | 0.788 | − 0.84 (− 1.94,0.26) | 0.136 |
Fully vaccinated | − 6.71 (− 8.64, − 4.78) | < 0.001 | − 190.60 (− 247.40, − 133.70) | < 0.001 | − 3.58 (− 4.47, − 2.70) | < 0.001 |
Time from illness onset to hospitalization | 0.20 (− 0.15,0.54) | 0.264 | 5.71 (− 4.44,15.85) | 0.271 | 0.06 (-0.10,0.22) | 0.492 |
Fever | 2.16 (0.25,4.07) | 0.027 | 65.94 (9.63,122.24) | 0.022 | 0.86 (− 0.03,1.76) | 0.060 |
Cough | 1.44 (− 0.34,3.23) | 0.113 | 44.25 (− 8.19,96.68) | 0.099 | 0.88 (0.05,1.71) | 0.039 |
Shortness of breath | 4.21 (− 0.72,9.15) | 0.095 | 113.13 (− 32.43,258.68) | 0.129 | 1.94 (− 0.37,4.25) | 0.101 |
C-reactive protein | 0.24 (0.18,0.29) | < 0.001 | 7.41 (5.82,8.99) | < 0.001 | 0.11 (0.08,0.13) | < 0.001 |
Interleukin-6 | 0.17 (0.14,0.20) | < 0.001 | 5.76 (4.90,6.63) | < 0.001 | 0.08 (0.06,0.09) | < 0.001 |
Lymphocyte count | − 4.17 (− 5.89, − 2.46) | < 0.001 | − 127.09 (− 177.4, − 76.77) | < 0.001 | − 2.29 (− 3.08, -1.50) | < 0.001 |
D-dimer | 0.31 (− 0.58,1.19) | 0.495 | 3.13 (− 22.94,29.19) | 0.814 | 0.19 (− 0.23,0.60) | 0.377 |
LDH | 0.05 (0.04,0.06) | < 0.001 | 1.34 (1.02,1.66) | < 0.001 | 0.02 (0.02,0.03) | < 0.001 |
SARS-COV-2 IgM | − 1.84 (− 3.00, − 0.68) | 0.002 | − 55.56 (− 89.60, − 21.53) | 0.002 | − 1.03 (− 1.57, − 0.49) | < 0.001 |
SARS-COV-2 IgG | − 2.59 (− 3.34, − 1.84) | < 0.001 | − 78.23 (− 100.23, − 56.23) | < 0.001 | − 1.39 (− 1.73, − 1.05) | < 0.001 |
N gene | − 0.05 (− 0.19, 0.09) | 0.521 | − 2.03 (− 6.15, 2.10) | 0.336 | − 0.04 (− 0.10, 0.03) | 0.250 |