Genetic contexts related to the diffusion of plasmid-mediated CTX-M-55 extended-spectrum beta-lactamase isolated from Enterobacteriaceae in China

Table 3 Antibiotic susceptibilities of bla_CTX-M-55-positive and their transconjugants

Isolate	Antibiotic^a susceptibility (μg/ml)
Isolate	SAM	TZP	CTX	CAZ	CTT	FEP	IPM	ETP	AMK	GEN	LVX	CIP
EC30	> 256	> 256	> 256	> 256	> 256	> 256	< 1	2	< 2	64	> 32	> 32
EC32	> 256	8	> 256	> 256	8	> 256	< 1	1	< 2	64	16	8
EC44	> 256	8	> 256	> 256	8	> 256	< 1	<0.5	< 2	32	16	8
EC45	> 256	64	> 256	> 256	32	> 256	< 1	<0.5	< 2	32	16	8
EC52	> 256	8	> 256	> 256	8	2	< 1	<0.5	< 2	64	> 32	8
EC54	> 256	8	> 256	> 256	8	16	< 1	<0.5	< 2	32	16	8
EC67	> 256	> 256	> 256	> 256	>256	> 256	< 1	2	< 2	32	> 32	8
KP26	> 256	64	> 256	> 256	32	> 256	< 1	1	< 2	32	> 32	8
KP37	> 256	> 256	> 256	> 256	> 256	> 256	8	2	< 2	32	16	8
KP146	> 256	64	> 256	> 256	> 256	> 256	8	2	< 2	64	> 32	8
CF547	> 256	8	> 256	64	8	> 256	< 1	< 0.5	< 2	64	16	8
MM556	> 256	64	> 256	> 256	> 256	2	< 1	< 0.5	< 2	32	16	8
SM554	> 256	8	> 256	64	8	> 256	8	< 0.5	4	32	16	8
E. coil transconjugants
EC30-C600	> 256	64	> 256	> 256	> 256	> 256	< 1	2	< 2	64	< 0.25	< 0.25
EC32-C600	> 256	8	> 256	> 256	8	8	< 1	1	< 2	32	< 0.25	< 0.25
EC44-C600	> 256	8	128	64	4	4	< 1	< 0.5	< 2	32	< 0.25	< 0.25
EC45-C600	> 256	32	> 256	> 256	32	16	< 1	< 0.5	< 2	16	< 0.25	< 0.25
EC52-C600	> 256	8	> 256	128	8	2	< 1	< 0.5	< 2	32	< 0.25	< 0.25
EC54-C600	> 256	8	128	> 256	8	16	< 1	< 0.5	< 2	32	< 0.25	< 0.25
EC67-C600	> 256	> 256	> 256	128	> 256	> 256	< 1	2	< 2	16	< 0.25	< 0.25
KP26-C600	> 256	32	> 256	> 256	16	8	< 1	1	< 2	32	< 0.25	< 0.25
KP37-C600	> 256	64	64	128	> 256	8	8	2	< 2	16	< 0.25	< 0.25
KP146-C600	> 256	32	> 256	> 256	> 256	> 256	8	2	< 2	64	< 0.25	< 0.25
CF547-C600	> 256	4	> 256	64	8	32	< 1	< 0.5	< 2	32	< 0.25	< 0.25
MM556-C600	> 256	64	64	> 256	> 256	2	< 1	< 0.5	< 2	16	< 0.25	< 0.25
SM554-C600	> 256	8	> 256	64	8	32	8	< 0.5	4	32	< 0.25	< 0.25
EC-C600	< 2	< 4	< 1	< 1	< 4	< 1	< 1	< 0.5	< 2	< 1	< 0.25	< 0.25

EC, E. coil; KP, K. pneumoniae; CF, C. freundii; MM, M. morganii; SM, S. marcescens
^aSAM, ampicillin–sulbactam (1/0.5–256/128) [(μg/ml) for each agent, and the numbers in parentheses indicate the test range]; TZP, piperacillin–tazobactam (0.5/4–256/4); CTX, cefotaxime (0.03–256); CAZ, ceftazidime (0.03–256); CTT, cefotetan (0.03–256); FEP, cefepime (0.015–256); IPM, imipenem (0.06–32); ETP, ertapenem (0.004–32); AMK, amikacin (0.5–256); GEN, gentamicin (0.25–256); LVX, levofloxacin (0.008–32); CIP, ciprofloxacin (0.004–32)

ISSN: 1476-0711