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Table 2 In vitro anti-bacterial and anti-biofilm activities of oxacillin and nisin against staphylococci studied

From: Combination antimicrobial therapy: in vitro synergistic effect of anti-staphylococcal drug oxacillin with antimicrobial peptide nisin against Staphylococcus epidermidis clinical isolates and Staphylococcus aureus biofilms

a Bacterial strain

Oxacillin

Nisin

MIC (µg/mL)

MBEC (µg/mL)

Fold change in MBEC/MIC ratio

MIC (µg/mL)

MBEC (µg/mL)

Fold change in MBEC/MIC ratio

SE1

4

8192

2048

128

2048

16

SE2

4

8192

2048

64

2048

32

SE3

8

2048

256

64

4096

64

SA ATCC 43,300

8

4096

512

64

4096

64

  1. MBEC: Minimum biofilm eradication concentration, MIC: Minimum inhibitory concentration
  2. a SA ATCC 43,300 is a mecA-positive, methicillin (oxacillin)-resistant Staphylococcus aureus (MRSA) reference strain and SE1, SE2, and SE3 were three clinical isolates of methicillin-resistant Staphylococcus epidermidis (MRSE)
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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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