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Table 3 Demographic and clinical characteristics of the 77 PCP patients according to herpesvirus detection

From: Pulmonary co-infections by Pneumocystis jirovecii and Herpesviridae: a seven-year retrospective study

 

PCP without HV

(n = 23)

PCP with at least

one HV (n = 54)

p

value

Mean age ± SD (years)

60.9 +/- 15.5

58.9 +/- 13.5

0.59*

Male sex, n (%)

14 (60.9)

36 (66.7)

0.90**

Underlying disease, n (%)

 

Hematological malignancy

11 (47.8)

26 (48.1)

0.97**

Solid organ or hematopoietic stem cell transplant

11 (47.8)

15 (27.8)

0.08**

Solid tumor

5 (21.7)

9 (16.7)

0.83**

Autoimmune disease

1 (4.3)

8 (14.8)

0.35**

Lung disease

1 (4.3)

6 (11.1)

0.60**

HIV infection

0 (0)

5 (9.3)

0.31**

Comorbidity, n (%)

   

Cardiovascular disease

10 (43.5)

22 (40.7)

0.82**

Diabetes

4 (17.4)

9 (16.6)

1**

Renal failure

4 (17.4)

5 (9.2)

0.52**

Immunosuppressive treatment, n (%)

   

Corticosteroids

7 (30.4)

15 (27.7)

0.81**

Cytotoxic chemotherapy

8 (34.8)

15 (27.7)

0.53**

Antiviral treatment, n (%)

6 (26)

18 (33.3)

0.04**

  1. Bold font indicates statistical significance
  2. HV, Herpesviridae; SD, standard deviation; PCP, Pneumocystis pneumonia
  3. *Student’s test
  4. **Chi-squared test