Table 1 Baseline characteristics of the study population
Characteristics | All transplantations | |||
|---|---|---|---|---|
Total (n = 57,103) | TB group (n = 830) | Non-TB group (n = 56,273) | P-value | |
Age at transplant (years) | ||||
0–19 | 4,851 (8.5) | 30 (3.6) | 4,821 (8.6) | < 0.001 |
20–39 | 9,884 (17.3) | 128 (15.4) | 9,756 (17.3) | |
40–59 | 31,783 (55.7) | 474 (57.1) | 31,309 (55.6) | |
> 60 | 10,585 (18.5) | 198 (23.9) | 10,387 (18.5) | |
Sex | ||||
Male | 35,123 (61.5) | 575 (69.3) | 34,548 (61.4) | < 0.001 |
Female | 21,980 (38.5) | 255 (30.7) | 21,725 (38.6) | |
Duration of follow-up (years) | 5.30 [3.54] | 1.75 [2.03] | 5.35 [3.53] | < 0.001 |
Comorbidities | ||||
Diabetes mellitus | 23,028 (40.3) | 377 (45.4) | 22,651 (40.3) | 0.003 |
Hypertension | 32,726 (57.3) | 485 (58.4) | 32,241 (57.3) | 0.51 |
Asthma | 7,841 (13.7) | 107 (12.9) | 7,734 (13.7) | 0.48 |
COPD | 3,186 (5.6) | 42 (5.1) | 3,144 (5.6) | 0.51 |
Liver Cirrhosis | 12,019 (21.0) | 198 (23.9) | 11,821 (21.0) | 0.05 |
Chronic kidney disease | 21,930 (38.4) | 319 (38.4) | 21,611 (38.4) | 0.99 |
Solid cancer | 12,696 (22.4) | 200 (24.1) | 12,496 (22.2) | 0.19 |
Hematologic malignancy | 12,547 (22.0) | 174 (21.0) | 12,373 (22.0) | 0.48 |
Autoimmune disease | 309 (0.5) | 1 (0.1) | 308 (0.5) | 0.14 |
Charlson Comorbidity Index | 5.48 [2.85] | 5.89 [2.95] | 5.48 [2.85] | < 0.001 |
Risk factors | ||||
Previous TB History | 1,741 (3.0) | 37 (4.5) | 1,704 (3.0) | 0.02 |
Pulmonary TB | 965 (1.7) | 27 (3.2) | 938 (1.7) | < 0.001 |
Extrapulmonary TB | 1,024 (1.8) | 15 (1.8) | 1,009 (1.8) | 0.98 |
Transplant type | ||||
SOT | 36,626 (64.1) | 554 (66.7) | 36,072 (64.1) | 0.003 |
Allogeneic HSCT | 11,202 (19.6) | 188 (22.7) | 11,014 (19.6) | 0.03 |
Autologous HSCT | 9,275 (16.2) | 88 (10.6) | 9,187 (16.3) | < 0.001 |
SOT transplant site | ||||
Kidneya | 20,904 (36.6) | 296 (35.7) | 20,608 (36.6) | 0.57 |
Heart | 1,373 (2.4) | 19 (2.3) | 1,354 (2.4) | 0.83 |
Liver | 13,568 (23.8) | 224 (27.0) | 13,344 (23.7) | 0.03 |
Lung | 600 (1.1) | 11 (1.3) | 589 (1.0) | 0.44 |
Othersb | 181 (0.3) | 4 (0.5) | 177 (0.3) | 0.39 |
Transplant year | ||||
2009 | 3,422 (6.0) | 99 (11.9) | 3,323 (5.9) | < 0.001 |
2010 | 3,687 (6.5) | 92 (11.1) | 3,595 (6.4) | |
2011 | 4,220 (7.4) | 100 (12.0) | 4,120 (7.3) | |
2012 | 4,481 (7.8) | 96 (11.6) | 4,385 (7.8) | |
2013 | 4,415 (7.7) | 80 (9.6) | 4,335 (7.7) | |
2014 | 4,713 (8.3) | 76 (9.2) | 4,637 (8.2) | |
2015 | 4,941 (8.7) | 59 (7.1) | 4,882 (8.7) | |