Effectiveness and safety of regimens containing linezolid for treatment of Mycobacterium abscessus pulmonary Disease

Table 4 Treatment outcomes of the linezolid and control groups.^*

Variable	Linezolid group (n = 164)	Control group (n = 172)	χ²	P value
Symptom relief
Cough	97 (79.5)	91 (65.5)	2.048	0.152
Expectoration	97 (79.5)	90 (64.7)	2.416	0.120
Fever	23 (92.0)	28 (93.3)	--	1.000^a
Hemoptysis	45 (68.2)	52 (65.0)	0.164	0.685
Dyspnea	17 (70.8)	21 (77.8)	0.323	0.570
Treatment Success	92 (56.1)	84 (48.8)	1.774	0.183
Culture conversion	88 (53.7)	80 (46.5)	1.715	0.190
Lesion change
Absorption	112 (68.3)	84 (48.8)	13.074	< 0.001
No change	32 (19.5)	42 (24.4)	1.177	0.278
Progression	20 (12.2)	46 (26.8)	11.258	0.001
Cavity change
No	6 (10.3)	12 (24.5)	3.798	0.051
Yes
Closure	32 (55.2)	14 (28.6)	7.669	0.006
Smaller	12 (20.7)	12 (24.5)	0.220	0.639
Larger or new	8 (13.8)	11 (22.4)	1.363	0.243

*Numbers indicate n (%)
^aP-value corrected using Fisher’s exact method when the expectation was below 5, --: no statistical value

ISSN: 1476-0711