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Table 4 Performances of inflammatory biomarkers in GP-BSI identification

From: PCT, IL-6, and IL-10 facilitate early diagnosis and pathogen classifications in bloodstream infection

Variable

CRP

PCT

IL-6

IL-10

ESR

WBC

NE %

PLT

AUC

0.5894

0.8277

0.7348

0.8592

0.5734

0.5096

0.5521

0.5195

P value

0.0064

< 0.0001

< 0.0001

< 0.0001

< 0.0278

0.7317

0.0618

0.484

Cut off

< 97.37

< 3.74

< 245.4

< 18.28

< 73.50

< 7.94

< 82.65

> 159.5

Sensitivity (%)

55.34

86.41

82.05

74.36

57.01

40.74

58.02

57.41

Specificity (%)

62.07

67.44

63.11

82.52

58.5

67.4

54.23

46.39

PPV (%)

27.54

51.45

45.71

61.7

36.75

38.82

39.17

36.67

NPV (%)

77.65

92.55

90.28

89.47

76.29

69.13

71.78

70.14

  1. AUC, Area under the receiver operating characteristic curve; PPV, positive predictive value; NPV, negative predictive value