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Table 2 Vaccine Efficacy and Effectiveness by Vaccine type and variant

From: The efficacy and effectiveness of COVID-19 vaccines around the world: a mini-review and meta-analysis

Efficacy or Effectiveness

Categories by vaccine or variant

No. Studies (Sample Size)

Pooled Efficacy

Between studies, heterogeneity assessment (%)

\({\text{I}}^{2}\)

P

1st Dose Efficacy

Astra

5

(634,638)

0.78 (0.62, 0.95)

77.09%

0.001

Pfizer

3

(733,805)

0.84 (0.77, 0.92)

89.97%

0.001

2nd Dose Efficacy

Astra

11 (92,653)

0.67 (0.54, 0.80)

79.99%

0.001

Pfizer

2 (113,651)

0.93 (0.85, 1.00)

-

-

Baharat

5

(70,028)

0.71 (0.61, 0.82)

88.30%

0.001

SARS COV2

1

(277)

0.70 (0.65, 0.76)

-

-

1st Dose Effectiveness

Moderna

9

(117,034)

0.74 (0.65, 0.83)

75.08%

0.043

Astra

5 (586,661)

0.69 (0.55, 0.82)

89.00%

0.001

Pfizer

3

(43,131)

0.67 (0.51, 0.83)

-

-

2nd Dose Effectiveness

Moderna

9

(117,034)

0.93 (0.89, 0.97)

73.40%

0.001

Astra

4

(405,357)

0.89 (0.80, 0.97)

89.03%

0.001

Pfizer

4

(43,570)

0.90 (0.83, 0.96)

44.32%

0.049

1st Dose Efficacy

Alpha

1

(108,720)

0.84 (0.84, 0.84)

-

-

Delta

1

(4360)

0.46 (0.45, 0.48)

-

-

Non-Beta

1

(1467)

0.75 (0.73, 0.78)

-

-

NR

2 (9862)

0.83 (0.72, 0.94)

 

-

2nd Dose Efficacy

Alpha

3 (134,916)

0.77 (0.57, 0.97)

99.97%

-

Beta

1 (1467)

0.10 (0.09, 0.12)

-

-

Non-Alpha

1 (8534)

0.77 (0.76, 0.78)

-

-

All Variants

1 (16,973)

0.71 (0.70, 0.71)

-

-

Delta

4 (23,746)

0.64 (0.58, 0.69)

97.39%

-

Gamma

2 (18,866)

0.68 (0.59, 0.77)

99.44%

-

NR

2 (9862)

0.93 (0.85, 1.00)

99.51%

-

Other

4 (52,812)

0.80 (0.69, 0.91)

99.91%

-

Undetermined

1 (9433)

0.57 (0.56, 0.58)

-

-

1st Dose Effectiveness

Alpha

5

(344,072)

0.74 (0.62, 0.86)

99.98%

-

Beta

1 (181,304)

0.61 (0.61, 0.62)

-

-

Delta

2

(6917)

0.65 (0.40, 0.89)

99.71%

-

Gamma

1 (5186)

0.74 (0.73, 0.75)

-

-

Other

4 (20,744)

0.74 (0.55, 0.93)

99.92%

-

Unidentified

1 (5186)

0.68 (0.66, 0.69)

-

-

Total

1 (181,304)

0.82 (0.81, 0.82)

-

-

2nd Dose Effectiveness

Alpha

3

(87,222)

0.86 (0.73–0.98)

99.97%

-

Beta

1 (181,304)

0.96 (0.96, 0.96)

-

-

Delta

3

(7160)

0.87 (0.82, 0.92)

95.59%

-

Gamma

1 (5186)

0.95 (0.95, 0.96)

-

-

Other

4 (20,744)

0.95 (0.92, 0.98)

99.24%

-

Unidentified

1 (5186)

0.80 (0.79, 0.81)

-

-

Total

1 (181,304)

0.96 (0.96, 0.96)

-

-

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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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