Table 1 Differences of characteristics between BDQR and BDQS MDR strains
Characteristics | No. (%) of isolates (n = 205) | No. (%) of isolates | |||
|---|---|---|---|---|---|
BDQR (n = 9) | BDQS (n = 196) | OR | P | ||
(95%CI) | |||||
Sex | |||||
Female | 55(26.8) | 3(33.3) | 52(26.5) | Ref. | |
Male | 150(73.2) | 6(66.7) | 144(73.5) | 0.72(0.17–2.99) | 0.95 |
Age (years) | |||||
≤ 40 | 69(33.7) | 4(44.4) | 65(33.2) | Ref. | |
41–59 | 96(46.8) | 3(33.3) | 93(47.4) | 0.52(0.11–2.42) | 0.65 |
≥ 60 | 40(19.5) | 2(22.2) | 38(19.4) | 0.86(0.15–4.89) | 1.00 |
Lineage | |||||
Lineage 4 | 37(18.0) | 0(0.0) | 37(18.9) | Ref. | |
Lineage 2 | 168(82.0) | 9(100.0) | 159(8.1) | 0.95(0.91–0.98) | 0.32 |
Genotype | |||||
Modern Beijing | 98(47.8) | 1(11.1) | 97(49.5) | Ref. | |
Ancient Beijing | 72(35.1) | 8(88.9) | 64(32.7) | 12.13(1.48–99.28) | < 0.01 |
Non-Beijing | 35(17.1) | 0(0.0) | 35(17.8) | 1.01(0.99–1.03) | 1.00 |
Treatment History | |||||
New case | 50(24.4) | 3(33.3) | 47(24.0) | Ref. | |
Re-treated | 155(75.6) | 6(66.7) | 149(76.0) | 0.63(0.15–2.62) | 0.81 |
Lung Cavitation | |||||
No | 124(60.5) | 6(66.7) | 118(60.2) | Ref | |
Yes | 81(39.5) | 3(33.3) | 78(39.8) | 0.76(0.18–3.11) | 0.97 |
Diabetes Mellitus | |||||
No | 192(93.7) | 7(77.8) | 185(94.4) | Ref. | |
Yes | 13(6.3) | 2(22.2) | 11(5.6) | 4.81(0.89–25.90) | 0.10 |
Previous exposure to | |||||
None | 16(7.8) | 1(11.1) | 15(7.7) | Ref. | |
FL drugs | 124(60.5) | 5(55.6) | 119(60.7) | 0.63(0.07–5.76) | 0.52 |
FL and SL drugs | 65(31.7) | 3(33.3) | 62(31.6) | 0.73(0.07–7.48) | 1.00 |
Resistance to | |||||
SM | 148(72.2) | 7(77.8) | 141(71.9) | 4.81(0.89–25.91) | 0.10 |
EMB | 77(37.6) | 5(55.6) | 72(36.7) | 2.15(0.56–8.28) | 0.43 |
OFX | 86(42.0) | 8(88.9) | 78(39.8) | 12.10(1.48–98.68) | < 0.01 |
KM | 30(14.6) | 1(11.1) | 29(14.8) | 0.72(0.09–5.97) | 1.00 |