Skip to main content

Table 3 Comparison of the clinical performance of the CRISPR-GBS with qPCR assay

From: CRISPR/Cas12a-based assay for the rapid and high-sensitivity detection of Streptococcus agalactiae colonization in pregnant women with premature rupture of membrane

 

CRISPR-GBS

Comparison of two methods

qPCR

Positive

Negative

Total

%OPAa

%PPAb

%NPAc

Positive

143

1

144

98.88 (96.02–99.69)d

99.31 (96.17–99.88)

97.14 (85.47–99.49)

Negative

1

34

35

   

Total

144

35

179

   
  1. aOPA, Overall percent agreement
  2. bPPA, Positive percent agreement
  3. cNPA, Negative percent agreement
  4. dValues in parentheses are the 95% CI, two-sided 95% confidence interval