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Table 1 Performance of CRISPR-GBS assay in clinical samples compared with culture-MS method

From: CRISPR/Cas12a-based assay for the rapid and high-sensitivity detection of Streptococcus agalactiae colonization in pregnant women with premature rupture of membrane

CRISPR-GBS assay

Culture-MS method

Comparison of two methods

Positive

Negative

Total

%Sensitivity

%Specificity

Kappa

Positive

144

0

144

96.64 (92.39–98.56)*

100 (88.65–100)

0.9061 (0.7603–1.052)

Negative

5

30

35

   

Total

149

30

179

   
  1. CRISPR-GBS CRISPR-based method for GBS detection, Culture-MS culture method combined with matrix-assisted laser desorption/ionization time-off light mass spectrometry
  2. *Values in parentheses are the 95% CI, two-sided 95% confidence interval