Variables | Case group (N = 18) | Control group (N = 36) | P-value |
---|---|---|---|
Demographics | Â | Â | Â |
Age (Median, IQR) | 38.5 (19–54.5) | 40 (20–54.5) |  |
Sex, male | 10 (55.6) | 20 (55.6) | Â |
Hospitalization | Â | Â | Â |
Length of stay, (IQR,days) | 52.5 (30.5–80.5) | 49.0 (21.0–91.0) | 0.783 |
Transferring from another hospital | 3 (16.7) | 8 (22.2) | 0.905 |
Admission to ICU | 6 (33.3) | 2 (5.6) | 0.021* |
Prior hospitalization | 13 (72.2) | 23 (63.9) | 0.540 |
Comobidity conditions | Â | Â | Â |
Diabetes mellitus | 2 (11.1) | 3 (8.3) | 1.000 |
Solid tumor | 2 (11.1) | 2 (5.6) | 0.854 |
Pneumonia | 14 (77.8) | 18 (50.0) | 0.050 |
Liver disease | 9 (50.0) | 10 (27.8) | 0.107 |
Gastritis | 4 (22.2) | 2 (5.6) | 0.168 |
Shock | 8 (44.4) | 9 (25.0) | 0.147 |
Diarrhea | 13 (72.2) | 13 (36.1) | 0.012* |
 | 7 (38.9) | 10 (27.8) | 0.407 |
Invasive procedures | Â | Â | Â |
Central venous catheter | 14 (77.8) | 30 (83.3) | 0.901 |
Arterial catheter | 4 (22.2) | 2 (5.6) | 0.168 |
Endotracheal intubation | 2 (11.1) | 3 (8.3) | 1.000 |
Mechanical ventilation | 10 (55.6) | 8 (22.2) | 0.014* |
Urinary catheter | 4 (22.2) | 2 (5.6) | 0.168 |
Nasogastric tube | 4 (22.2) | 1 (2.8) | 0.068 |
HSCT | 5 (27.8) | 15 (41.7) | 0.319 |
Drug exposure | Â | Â | Â |
PPIs | 15 (83.3) | 18 (50.0) | 0.018* |
Glucocorticoid | 13 (72.2) | 19 (52.8) | 0.170 |
Cephalosporins | 6 (33.3) | 4 (11.1) | 0.107 |
Carbapenems | 17 (94.4) | 26 (72.2) | 0.120 |
Fluoroquinolones | 9 (50.0) | 19 (52.8) | 0.847 |
Glycopeptides | 9 (50.0) | 16 (44.4) | 0.700 |
Tigecycline | 8 (44.4) | 11 (30.6) | 0.314 |
Oxazolidones | 6 (33.3) | 10 (27.8) | 0.673 |
Aminoglycosides | 3 (16.7) | 7 (19.4) | 1.000 |
β-lactam/β-lactamase inhibitors | 12 (66.7) | 21 (58.3) | 0.554 |
Macrolides | 2 (11.1) | 4 (11.1) | 1.000 |
Antifungal agents | 14 (77.8) | 31 (86.1) | 0.699 |
Antiviral agents | 7 (38.9) | 17 (47.2) | 0.561 |
CRE isolates | Â | Â | Â |
Klebsiella pneumoniae | 10 (55.6) | 17 (47.2) | 0.564 |
Escherichia coli | 6 (33.3) | 9 (25.0) | 0.519 |
Enterobacter cloacae | 1 (5.6) | 4 (11.1) | 0.868 |
others | 1 (5.6) | 6(2.8) | 0.64 |
Types of hematological malignancy | Â | Â | Â |
AML | 8 (44.4) | 18 (50.0) | 0.700 |
ALL | 6 (33.3) | 7 (19.4) | 0.260 |
MM | 0 (0.0) | 2 (5.6) | 0.313 |
Lymphoma | 4 (22.2) | 7 (19.4) | 1.000 |
others | 0 (0.0) | 2 (5.6) | 0.313 |