Maternal colonization with group B Streptococcus and antibiotic resistance in China: systematic review and meta-analyses

Table 4 Comparison of drug resistance rates from 2017 to 2021 of China

Antibiotics		2017	2018	2019	2020	2021	χ²	p-value
Erythromycin	No. of GBS isolates	2218	1373	2774	3039	3764	39.333	< 0.001
Erythromycin	Drug resistance rate (%)	73.69	74.38	72.69	69.21^abc	74.51^d	39.333	< 0.001
Clindamycin	No. of GBS isolates	1987	1178	2351	2409	3016	75.857	< 0.001
Clindamycin	Drug resistance rate (%)	66.01	63.81	61.61^a	56.71^abc	59.70^abd	75.857	< 0.001
Levofloxacin	No. of GBS isolates	1613	1061	1946	2029	2420	92.400	< 0.001
Levofloxacin	Drug resistance rate (%)	53.59	57.48^a	51.00^ab	46.21^abc	47.90^abc	92.400	< 0.001

^aCompared with 2017, P < 0.05. ^bCompared with 2018, P < 0.05. ^cCompared with 2019, P < 0.05. ^dCompared with 2020, P < 0.05

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