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Table 4 Multivariable logistic regression of factors associated with mixed C/B-BSIs

From: Incidence, clinical characteristics, risk factors and outcomes of patients with mixed Candida/bacterial bloodstream infections: a retrospective study

Risk factors

B

S.E

Wald

P value

aOR (95% CI)

Prior hospital stay (days)

0.00

0.01

0.02

0.88

1.00 (0.99–1.01)

Prior antibiotic exposure

0.88

0.53

2.76

0.10

2.42 (0.85–6.85)

Prior β-lactams exposure

0.68

0.34

3.93

0.05

1.97 (1.01–3.87)

Initial antifungal agent was Echinocandin

0.56

0.33

3.01

0.08

1.76 (0.93–3.33)

Prior ICU stay (days)

0.01

0.01

1.15

0.28

1.01 (0.99–1.02)

Burn injury

1.85

0.64

8.38

 < 0.01

6.35 (1.82–22.21)

ECMO

1.15

1.20

0.92

0.34

3.16 (0.30–33.31)

CRRT

1.10

0.37

8.88

 < 0.01

3.00 (1.46–6.17)

Invasive mechanical ventilation

0.24

0.43

0.31

0.58

1.27 (0.54–2.98)

Total parenteral nutrition

0.64

0.36

3.10

0.08

1.89 (0.93–3.85)

Blood transfusion

0.39

0.33

1.45

0.23

1.48 (0.78–2.81)

ICU admission

-0.52

0.43

1.41

0.24

0.60 (0.25–1.40)

Lactic acid

0.06

0.06

0.87

0.35

1.06 (0.94–1.19)

Procalcitonin

0.02

0.01

2.34

0.13

1.02 (0.99–1.04)

SOFA score

0.03

0.05

0.48

0.49

1.03 (0.94–1.14)

Peripheral arterial catheters

-0.22

0.37

0.33

0.56

0.81 (0.39–1.68)

Thoracic drainage tube

0.56

0.40

1.95

0.16

1.75 (0.80–3.85)

Constant

-3.86

0.64

36.68

 < 0.01

0.02 (–)

  1. Bold, indicates P < 0.05
  2. B coefficient; SE standard error; Wald wald test statistic; OR odds ratio; CI confidence interval; ICU intensive care unit; ECMO extracorporeal membrane oxygenation; CRRT continuous renal replacement therapy; SOFA Sequential Organ Failure Assessment