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Table 3 Comparison of biological indicators between groups of mono-candidemia and mixed C/B-BSIs

From: Incidence, clinical characteristics, risk factors and outcomes of patients with mixed Candida/bacterial bloodstream infections: a retrospective study

Biological indicators

Total

(n = 296)

Mono-candidemia

(n = 218)

Mixed C/B-BSIs

(n = 78)

P value

Procalcitonin (ng/L) (IQR)

0.7 (0.3–2.3)

0.6 (0.2–1.6)

1.2 (0.4–7.0)

 < 0.01

CRP (mg/L) (IQR)

82.8 (46.6–151.6)

78.5 (42.0–136.8)

90.0 (58.4–171.8)

0.04

1,3-β-D glucan test [n (%)]

96 (32.4)

   

 Positive

34 (11.5)

24 (11.0)

10 (12.8)

0.67

 Negative

62 (20.9)

39 (17.9)

23 (29.5)

0.03

Liver and kidney function

    

 GPT (U/L) (IQR)

32.0 (20.0–63.5)

32.0 (21.0–59.3)

36.0 (16.8–82.8)

0.66

 GOT (U/L) (IQR)

39.0 (25.0–64.5)

36.0 (24.8–57.0)

44.0 (27.8–99.0)

0.02

 Albumin (g/L) (mean ± S.D.)

30.7 ± 5.8

31.0 ± 5.8

29.8 ± 5.8

0.15

 TBil (μmol/L) (IQR)

16.0 (11.0–30.5)

15.0 (10.0–29.2)

17.0 (11.0–37.0)

0.06

 BUN (mmol/L) (IQR)

8.4 (5.1–14.3)

8.1 (4.9–14.9)

8.8 (5.4–12.7)

0.88

 SCr (μmol/L) (IQR)

61.0 (40.0–95.8)

59.0 (39.8–93.3)

67.0 (41.8–101.0)

0.39

Blood routine test

    

 WBC (× 109/L) (IQR)

9.5 (5.8–14.0)

9.2 (5.6–13.2)

10.0 (6.7–15.0)

0.19

 Hemoglobin (g/L) (IQR)

82.0 (71.0–95.0)

83.0 (71.0–99.3)

80.0 (68.0–90.3)

0.06

 Hematocrit (%) (IQR)

24.4 (21.0–29.0)

25.0 (21.0–30.0)

24.0 (21.0–27.0)

0.05

 Platelet (× 109/L) (IQR)

130.0 (70.0–230.5)

134.5 (75.8–229.5)

116.5 (46.0–245.0)

0.28

Lactic acid (mmol/L) (IQR)

1.5 (1.0–2.5)

1.5 (1.0–2.3)

1.8 (1.2–3.2)

0.02

  1. The time point for the biological indicators was on the day of submission of the first positive blood culture sample of candida
  2. Bold, indicates p < 0.05
  3. IQR interquartile range; CRP C−reactive protein; GPT glutamic−pyruvic transaminase; GOT glutamic−oxaloacetic transaminase; TBil total bilirubin; BUN blood urea nitrogen; SCr serum creatinine; WBC white blood count