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Table 5 The sensitivity and specificity rates of CFM for screening of ESBL using disk diffusion method at deferent breakpoints and for CFM-AMC DDST at different synergy distances

From: Cefixime and cefixime-clavulanate for screening and confirmation of extended-spectrum beta-lactamases in Escherichia coli

Test Breakpoint Sensitivity (%) Specificity (%)
ESBL screening ≤ 14 mm 81.3 64.7
≤ 15 mm 83.3 64.7
≤ 16 mm 84.7 64.7
≤ 17 mm 87.2 64.7
≤ 18 mm 87.8 64.7
≤ 19 mm 88.2 64.7
≤ 20 mm 88.7 64.7
≤ 21 mm 89.2 64.7
Double-disk synergy test Distance Sensitivity (%) Specificity (%)
≥ 1 mm 75.4 75.8
≥ 3 mm 71.3 75.8
≥ 5 mm 63.3 75.8