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Table 5 The sensitivity and specificity rates of CFM for screening of ESBL using disk diffusion method at deferent breakpoints and for CFM-AMC DDST at different synergy distances

From: Cefixime and cefixime-clavulanate for screening and confirmation of extended-spectrum beta-lactamases in Escherichia coli

Test

Breakpoint

Sensitivity (%)

Specificity (%)

ESBL screening

≤ 14 mm

81.3

64.7

≤ 15 mm

83.3

64.7

≤ 16 mm

84.7

64.7

≤ 17 mm

87.2

64.7

≤ 18 mm

87.8

64.7

≤ 19 mm

88.2

64.7

≤ 20 mm

88.7

64.7

≤ 21 mm

89.2

64.7

Double-disk synergy test

Distance

Sensitivity (%)

Specificity (%)

≥ 1 mm

75.4

75.8

≥ 3 mm

71.3

75.8

≥ 5 mm

63.3

75.8