Table 1 Clinical characteristics of the episodes (N = 514 episodes)
Characteristic | Sepsis-3 positivea/Sepsis-2 positive (n = 341) | Sepsis-3 negative/Sepsis-2 positive (n = 70) | Sepsis-3 positive/Sepsis-2 negative (n = 16) | Sepsis-3 negative/Sepsis-2 negative (n = 87) |
|---|---|---|---|---|
Demographics | ||||
Male—n (%) | 209 (61.3) | 42 (60.0) | 10 (62.5) | 50 (57.5) |
Age—yearsb | 73.2 (14.0) | 60.2 (19.5) | 71.6 (15.8) | 60.8 (20.3) |
28-day mortality n (%) | 54 (15.8) | 5 (7.1) | 1 (6.3) | 8 (9.2) |
Admission to intensive care unit during hospital stay, n (%) | 38 (11.1) | 1 (1.4) | 3 (18.8) | 2 (2.3) |
SOFA scorec | 3 (3–5) | 1 (1–2) | 3.5 (2–6) | 2 (1–3) |
Co-morbidities, n () | ||||
Congestive heart failure | 66 (19.4) | 8 (11.4) | 4 (25.0) | 9 (10.3) |
Diabetes mellitus | 101 (29.6) | 15 (21.4) | 4 (25.0) | 32 (36.8) |
Ischemic heart disease | 50 (14.7) | 5 (7.1) | 2 (12.5) | 7 (8.0) |
Peripheral vascular disease | 35 (10.3) | 4 (5.7) | 0 (0.0) | 5 (5.7) |
Cerebrovascular disease | 74 (21.7) | 9 (12.9) | 3 (18.8) | 12 (13.8) |
Malignancy | 86 (25.2) | 9 (12.9) | 5 (31.3) | 14 (16.1) |
Chronic kidney failure (GFR < 60) | 98 (28.7) | 8 (11.4) | 4 (25.0) | 16 (18.4) |
Chronic pulmonary disease | 52 (15.2) | 18 (25.7) | 2 (12.5) | 10 (11.5) |
Chronic liver failure | 9 (2.6) | 2 (2.9) | 1 (6.3) | 3 (3.4) |
Source of infectiond | ||||
Respiratory tract | 127 (37.2) | 25 (35.7) | 6 (37.5) | 2 (2.3) |
Urinary tract | 80 (23.5) | 15 (21.4) | 4 (25.0) | 0 (0.0) |
Abdominal | 27 (7.9) | 5 (7.1) | 0 (0.0) | 2 (2.3) |
Soft tissue/skin/skeletal/joint | 26 (7.6) | 10 (14.3) | 2 (12.5) | 0 (0.0) |
Central nervous system | 2 (0.6) | 0 (0.0) | 1 (6.3) | 1 (1.1) |
Endocarditis | 5 (1.5) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Other/unknown | 81 (23.8) | 15 (21.4) | 3 (18.8) | 1 (1.1) |
No suspected infection | N/A | N/A | N/A | 81 (93.1) |