From: Comparative evaluation of six nucleic acid amplification kits for SARS-CoV-2 RNA detection
No. of RT-qPCR result | No. of clinical diagnostic report | Sensitivity | Specificity | PPV | NPV | Diagnostic accuracy | Kappa | ||
---|---|---|---|---|---|---|---|---|---|
Positive | Negative | (95% CI) | (95% CI) | (95% CI) | (95% CI) | (95% CI) | |||
A | Positive | 26 | 0 | 100 (87.1–100) | 100 (87.1–100) | 100 (87.1–100) | 100 (87.1–100) | 100 | 1 |
Negative | 0 | 26 | (93.1–100) | (p < 0.001) | |||||
B | Positive | 23 | 0 | 100 (85.7–100) | 89.7 (73.6–96.4) | 88.5 (71.0–96.0) | 100 (87.1–100) | 94.2 | 0.885 |
Negative | 3 | 26 | (84.4–98.0) | (p < 0.001) | |||||
C | Positive | 25 | 0 | 100 (86.7–100) | 96.3 (81.7–99.3) | 96.2 (81.1–99.3) | 100 (87.1–100) | 98.1 | 0.962 |
Negative | 1 | 26 | (89.9–99.7) | (p < 0.001) | |||||
D | Positive | 18 | 0 | 100 (82.4–100) | 76.5 (60.0–87.6) | 69.2 (50.0–83.5) | 100 (87.1–100) | 84.6 | 0.692 |
Negative | 8 | 26 | (72.5–92.0) | (p < 0.001) | |||||
E | Positive | 20 | 0 | 100 (83.9–100) | 81.3 (64.7–91.1) | 76.9 (57.6–89.0) | 100 (87.1–100) | 88.5 | 0.769 |
Negative | 6 | 26 | (77.0–94.6) | (p < 0.001) | |||||
F | Positive | 24 | 0 | 100 (86.2–100) | 92.9 (77.4–98.0) | 92.3 (75.9–97.9) | 100 (87.1–100) | 96.15 | 0.923 |
Negative | 2 | 26 | (87.0–98.9) | (p < 0.001) |