Patient characteristics | Group RBT 150 mg TPW (n = 9) | Group RBT 300 mg TPW (n = 7) | p |
---|---|---|---|
Age (years) | 36.3 ± 6.70 | 34.7 ± 6.92 | 0.643 |
Sex | |||
Male | 6/9 | 2/7 | 0.131 |
Female | 3/9 | 5/7 | |
Weight (kg) | 51 ± 11.88 | 49.7 ± 8.80 | 0.832 |
Body mass index (BMI) | 18.0 ± 3.74 | 17.1 ± 2,37 | 0.604 |
Dose of lopinavir (mg)/kg/12 h | 8.07 ± 1.41 | 8. 51 ± 1.44 | |
Dose of ritonavir (mg)/kg/12 h | 2.02 ± 0.35 | 2.13 ± 0.36 | |
Laboratory parameters | |||
Haemoglobin (g/dL) | 10.3 ± 3.58 | 9.8 ± 1.45 | 0.802 |
Leucocytes (103/mL) | 4960 ± 3050 | 3900 ± 1643 | 0.554 |
Neutrophils (103/mL) | 3890 ± 1935 | 3956 ± 2985 | |
Lymphocytes (103/mL) | 1420 ± 837 | 1375 ± 801 | 0.937 |
Monocytes (103/mL) | 260 ± 89 | 225 ± 189 | 0.722 |
AST (U/L) | 61.8 ± 20.31 | 48.2 ± 37.44 | 0.507 |
ALT (U/L) | 49.4 ± 34.28 | 30 ± 22.31 | 0.363 |
Creatinine (µmol/L) | 102.2 ± 27.54 | 106.1 ± 62.01 | 0.926 |
Total cholesterol (mmol/L) | 162 ± 29.10 | 104.3 ± 58.44 | 0.200 |
HDL cholesterol (mmol/L) | 24.3 ± 10.26 | 23 ± 9.89 | 0.894 |
Amylasaemia (U/L) | 116.6 ± 18.03 | 98 ± 56.78 | 0.616 |
Total bilirubin (µmol/L) | 6.2 ± 2.70 | 9.2 ± 4.80 | 0.360 |
Direct bilirubin (µmol/L) | 0.87 ± 1.02 | 2.75 ± 2.33 | 0.213 |
Lymphocytes TCD4 (cells/µL) | 221.1 ± 154.75 | 285.8 ± 175.39 | 0.446 |
Type of tuberculosis | |||
SPPT | 7/9 | 7/7 | 0.475 |
SNPT | 2/9 | 0/7) | – |
WHO HIV stage | |||
Stage 2 | 1/9 | 0/7 | 0.562 |
Stage 3 | 8/9 | 7/7 |