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Table 6 Distribution of antibiotic resistance among uropathogens isolated from the study group

From: Multi-drug resistant and extended-spectrum β-lactamases producing bacterial uropathogens among pregnant women in Northwest Ethiopia

Antibiotics tested

Isolated organisms (n = 61)

Total (61)

Enterobacteriaceae (n = 33)

E. coli (n = 30)

K. pneumoniae (n = 2)

E. cloacae (n = 1)

S. aureus (n = 11)

CoNS (n = 17)

Non-ESβLs (n = 27)

ESβLs (n = 6)

p-value

AUG

17 (56.67%)

1 (50%)

1

19/33 (57.6%)

15 (55.6%)

4 (66.7%)

0.618

FEP

6 (20%)

0

1

7/33 (21.2%)

1 (3.7%)

6 (100%)

< 0.001

CFM

6 (20%)

0

1

7/33 (21.2%)

1 (3.7%)

6 (100%)

< 0.001

CRO

5 (16.67%)

0

1

6/33 (18.2%)

0 (0.0%)

6 (100%)

< 0.001

FOX

3 (10%)

0

1

4 (36.36%)

8 (47.05%)

18/61 (26.2%)

1(3.7%)

3 (50%)

0.014

CXM

5 (16.67%)

0

1

6/33 (18.2%)

0 (0.0%)

6 (100%)

< 0.001

AMP

27 (90%)

2 (100%)

1

30/33 (90.9%)

24 (88.9%)

6 (100%)

0.392

NAL

5 (16.67%)

0

1

6/33 (18.2%)

2 (7.4%)

4 (66.7%)

0.005

CF

25 (83.33%)

2 (100%)

1

28/33 (84.8%)

22 (81.5%)

6 (100%)

0.556

CPD

5 (16.67%)

0

1

6/33 (18.2%)

0 (0.0%)

6 (100%)

< 0.001

CAZ

5 (16.67%)

0

1

6/33 (18.2%)

0 (0.0%)

6 (100%)

< 0.001

NOR

4 (13.33%)

0

0

1 (9.1%)

8 (47.05%)

13/61 (21.3%)

2 (7.4%)

2 (33.33%)

0.142

F

0

0

0

0

1 (5.9%)

1/61 (1.64%)

0 (0.0%)

0 (0.0%)

CIP

4 (13.33%)

0

0

1 (9.1%)

8 (47.05%)

13/61 (21.3%)

2 (7.4%)

2 (33.33%)

0.142

CTX

5 (16.67%)

0

1

6/33 (18.2%)

0 (0.0%)

6 (100%)

< 0.001

GEN

0

0

0/28 (0.0%)

PEN

10 (90.9%)

15 (88.2%)

25/28 (89.3%)

TE

2 (18.18%)

9 (52.9%)

11/28 (39.3%)

COT

7 (63.63%)

14 (82.35%)

21/28 (75%)

AMK

0

0

0/28 (0.0%)

DOX

2 (18.18%)

10 (58.82%)

12/28 (42.68%)

C

3 (27.27%)

9 (52.9%)

12/28 (42.68%)

ERY

2 (18.18%)

9 (52.9%)

11/28 (39.3%)

  1. Italic values means the observed difference is statistically significant (p < 0.05)
  2. “–“ Not done; AUG, amox-clavulanic acid; FEP, cefepime; CFM, cefixime; CRO, ceftriaxone; FOX, cefoxitin; CXM, cefuroxime; AMP, ampicillin; NAL, nalidixic acid; CF, cephalothin; CPD, cefpodoxime; CAZ, ceftazidime; NOR, norfloxacin; F, nitrofurantoin; CIP, ciprofloxacin; CTX, cefotaxime; PEN, penicillin; TE, tetracycline; COT, cotrimoxazole; AMK, amikacin; DOX, doxycycline; C, chloramphenicol, and ERY, erythromycin