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Table 4 Relationship between biofilm production and drug resistance

From: Investigation of biofilm production and its association with genetic and phenotypic characteristics of OM (osteomyelitis) and non-OM orthopedic Staphylococcus aureus

Strain traitTotal (n = 137)OM (n = 60)Non-OM (n = 77)
N (%), P valuea
MRSA30 (21.9), 0.038 (rho =−0.169, P = 0.048)b9 (15.0), 0.55321 (27.3), 0.042 (rho = −0.238, P = 0.037)b
MDR40 (29.2), 0.08918 (30.0), 0.11322 (28.6), 0.387
CIP-resistant12 (8.8), 0.5336 (10.0), 0.6416 (7.8), 0.191
CLI-resistant62 (45.3), 0.15127 (45.0), 0.20235 (45.5), 0.417
ERY-resistant67 (48.9), 0.24527 (45.0), 0.39040 (51.9), 0.454
GEN-resistant12 (8.8), 0.4556 (10.0), 0.7116 (7.8), 0.133
LVX-resistant10 (7.3), 0.2604 (6.7), 0.5986 (7.8), 0.368
MFX-resistant9 (6.6), 0.5284 (6.7), 0.8765 (6.5), 0.416
OXA-resistant32 (23.4), 0.45613 (21.7), 0.39519 (24.7), 0.776
PEN-resistant125 (91.2), 0.88853 (88.3), 0.34072 (93.5), 0.367
RIF-resistant7 (5.1), 0.1215 (8.3), 0.2562 (2.6), 0.836
SXT-resistant13 (9.5), 0.9464 (6.7), 0.1099 (11.7), 0.318
TCY-resistant38 (27.7), 0.031 (rho = −0.185, P = 0.031)b21 (35.0), 0.09817 (22.1), 0.133
  1. All the strains were susceptible to LNZ, TGC and VAN. Significant differences are in italics
  2. aBy Mann–Whitney U test, comparing biofilm production (OD492 values) between resistant and non-resistant strains in each group
  3. bSignificant factors were further subjected to spearman correlation analyses