Fig. 5

SAAP-148 against different bacterial loads of MRSA. The effect of 7.6 nmol SAAP-148 in PBS on different bacterial loads. a In vitro killing of 10³, 10⁵, 10⁶ or 10⁷ CFU MRSA by 10 µL of PBS or SAAP-148 in PBS after 30 min incubation. b Ex vivo excision wounds were inoculated with 10³, 10⁵, 10⁶ or 10⁷ CFU MRSA for 1 h and exposed to 10 µL of SAAP-148 in PBS or PBS for 1 h. Results are expressed as the LR. Data represent the mean of six independent experiments performed in triplicate. * indicates significant difference (*p < 0.05; **p < 0.01) as compared to the LR caused by SAAP-148 at 10⁷ CFU MRSA