Table 1 Clinical and microbiological characteristics, host response and nutritional status of hvKp
Characteristic | HvKp (80) | cKp (95) | P value |
|---|---|---|---|
K serotype | |||
K1 | 26 (32.5%) | 3 (3.2%) | 0.000 |
K2 | 11 (13.8%) | 1 (1.1%) | 0.001 |
K5 | 1 (1.3%) | 0 (0%) | 0.276 |
K20 | 2 (2.5%) | 5 (5.3%) | 0.354 |
K54 | 2 (2.5%) | 3 (3.2%) | 0.795 |
K57 | 6 (7.5%) | 7 (7.4%) | 0.974 |
rmpA | 65 (81.3%) | 17 (17.9%) | 0.000 |
rmpA2 | 58 (72.5%) | 19 (20.0%) | 0.000 |
magA | 63 (78.8%) | 58 (61.1%) | 0.012 |
Basic demographics | |||
Age | 83.2 ± 8.75 | 86.2 ± 8.04 | 0.020 |
Male | 77 (96.3%) | 92 (96.8%) | 0.837 |
Underlying diseases | |||
Pulmonary disease | 73 (91.3%) | 90 (94.7%) | 0.363 |
Diabetes | 61 (76.3%) | 52 (54.7%) | 0.003 |
Cardiovascular disease | 40 (50.0%) | 58 (61.1%) | 0.142 |
Cerebrovascular disease | 9 (11.3%) | 20 (21.1%) | 0.082 |
Cancer | 21 (26.3%) | 28 (29.5%) | 0.636 |
Surgery within 1 mo | 6 (7.5%) | 11 (11.6%) | 0.364 |
Digestive disease | 25 (31.3%) | 20 (21.1%) | 0.124 |
Catheter | |||
Central intravenous catheter | 50 (62.5%) | 65 (68.4%) | 0.411 |
Urinary catheter | 57 (71.3%) | 79 (83.2%) | 0.059 |
Tracheal catheter | 24 (30.0%) | 33 (34.7%) | 0.505 |
Stomach tube | 45 (56.3%) | 71 (74.7%) | 0.01 |
Drainage tube | 4 (5.0%) | 1 (1.1%) | 0.119 |
Infection type | |||
HAP | 62 (77.5%) | 68 (71.6%) | 0.372 |
Urinary infection | 8 (10.0%) | 20 (21.1%) | 0.047 |
Invasive infection | 23 (28.8%) | 6 (6.3%) | 0.000 |
Bacteraemia | 5 (6.3%) | 4 (4.2%) | 0.543 |
Liver abscess | 8 (10.0%) | 1 (1.1%) | 0.008 |
Other abscess | 13 (16.3%) | 3 (3.2%) | 0.003 |
Abdominal infection | 18 (22.5%) | 6 (6.3%) | 0.002 |
Sepsis | 41 (51.3%) | 40 (42.1%) | 0.227 |
Septic shock | 9 (11.3%) | 3 (3.2%) | 0.035 |
Host response | |||
WBC | 12.87 ± 4.24 | 10.34 ± 2.95 | 0.000 |
NEU% | 78.87 ± 7.60 | 74.23 ± 7.83 | 0.000 |
Nutrition status | |||
TP | 65.14 ± 4.93 | 62.96 ± 4.71 | 0.003 |
ALB | 35.54 ± 2.75 | 34.45 ± 3.44 | 0.021 |
SOFA score | 6.84 ± 2.81 | 4.93 ± 2.59 | 0.000 |
Infection occurred in ICU | 13 (16.3%) | 14 (14.7%) | 0.783 |
Relapse | 5 (6.3%) | 5 (5.3%) | 0.779 |
Mortality at 28 days | 14 (17.5%) | 17 (17.9%) | 0.946 |