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Table 3 The eradication rates of empirical eradication therapy

From: Vonoprazan-based triple therapy is non-inferior to susceptibility-guided proton pump inhibitor-based triple therapy for Helicobacter pylori eradication

 

PPI + AC

P − CAB + AC vonoprazan

n = 363

Esomeprazole

n = 123

Rabeprazole

n = 450

Lansoprazole

n = 207

Total

n = 780

Intention to treat

100/123

359/450

160/207

619/780

332/363

% (95% CI)

81.3 (74.4–88.2)

79.8 (76.1–83.5)

77.3 (71.6–83.0)

79.4 (76.5–82.2)

91.5 (88.6–94.3)

Per protocol

100/113

359/417

160/187

619/717

332/341

% (95% CI)

88.5 (82.6–94.4)

86.1 (82.8–89.4)

85.6 (80.5–90.6)

86.3 (83.8–88.8)

97.4 (95.7–99.1)

  1. PPI + AC proton pump inhibitor with amoxicillin and clarithromycin, P − CAB + AC potassium-competitive acid blocker with amoxicillin and clarithromycin