Table 2 Clinical characteristics of the outbreak cases and antimicrobial susceptibility profiles of Providencia rettgeri isolates
Patient ID | P1 | P2 | P3 | P4 | P5 | P6 | P7 | P8 |
|---|---|---|---|---|---|---|---|---|
Isolate no. | KN756 | KN762 | KN764 | KN774 | KN779 | KN784 | KN803 | KN804 |
Sex/age (year) | M/63 | M/50 | M/52 | M/66 | F/75 | M/81 | F/40 | M/53 |
Diagnosis | Brain hemorrhage | Deep neck infection | Central nervous system infection | Bladder cancer | Pneumonia | Pneumonia | Brain hemorrhage | Brain hemorrhage |
Comorbidities | – | Diabetes mellitus | – | – | Cerebral infarction | Diabetes mellitus | – | – |
Outcome | Survival | Survival | Survival | Survival | Death | Survival | Survival | Survival |
Hospital admission date | 18-Dec-15 | 05-Apr-16 | 28-Apr-16 | 01-Jul-16 | 28-Jul-16 | 14-Aug-16 | 16-Dec-16 | 19-Dec-16 |
P. rettgeri collection date | 11-Jan-16 | 09-May-16 | 19-May-16 | 08-Aug-16 | 19-Aug-16 | 22-Aug-16 | 30-Dec-16 | 05-Jan-17 |
Antimicrobial agents used before P. rettgeri isolation (days) | Colistin (13), piperacillin-tazobactam (8), teicoplanin (11) | Colistin (21), metronidazole (10), piperacillin-tazobactam (10), ampicillin-sulbactam (3), teicoplanin (20), netilmicin (5), levofloxacin (9) | Colistin (13), piperacillin-tazobactam (3), vancomycin (8), teicoplanin (13), meropenem (7) | Ceftriaxone (6), tigecycline (4), doripenem (7), piperacillin-tazobactam (18), flomoxef (3), teicoplanin (5) | Metronidazole (10), moxifloxacin (6), piperacillin-tazobactam (2), teicoplanin (2) | Piperacillin-tazobactam (5), ampicillin-sulbactam (3) | Ceftriaxone (3) | Ceftriaxone (8) |
MIC (μg/mL) | ||||||||
Cefotetan | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 |
Cefotaxime | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 |
Ceftazidime | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 |
Cefepime | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 |
Aztreonam | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 |
Imipenem | 0.5 | 0.5 | 2 | 4 | 0.5 | 1 | 0.5 | 0.5 |
Meropenem | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 |
Ertapenem | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 |
Ciprofloxacin | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 |
Amikacin | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 | > 256 |
Gentamicin | 8 | 16 | 16 | 16 | 8 | 16 | 8 | 8 |
Tigecycline | 4 | 4 | 4 | 8 | 4 | 8 | 8 | 8 |
Colistin | 2 | 2 | 8 | 2 | 2 | 64 | 4 | 4 |