Table 5 Directed antimicrobial agents stratified by type of infection
Directed antimicrobial therapy | Number (%) of patients | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Infection type | |||||||||
VABP (N = 31) | Bacteremia (N = 22) | cUTI/AP (N = 18) | HABP (N = 16) | SWI (N = 16) | BTI (N = 9) | DWI (N = 7) | SBFI (N = 5) | All (N = 124) | |
No treatment | 2 (6.5%) | 1 (4.5%) | 1 (5.6%) | 1 (6.3%) | 3 (18.8%) | 1 (11.1%) | 1 (14.3%) | 0 | 10 (8.1%) |
No Gram-negative coverage | 0 | 0 | 0 | 0 | 1 (6.3%) | 0 | 1 (14.3%) | 0 | 2 (1.6%) |
Gram-negative therapy | 29 (93.5%) | 21 (95.5%) | 17 (94.4%) | 15 (93.8%) | 12 (75.0%) | 8 (88.9%) | 5 (71.4%) | 5 (100%) | 112 (90.3%) |
Monotherapy | 3 (9.7%) | 1 (4.5%) | 12 (66.7%) | 5 (31.3%) | 6 (37.5%) | 2 (22.2%) | 1 (14.3%) | 1 (20.0%) | 31 (25.0%) |
Dual therapy | 13 (41.9%) | 8 (36.4%) | 5 (27.8%) | 8 (50.0%) | 6 (37.5%) | 5 (55.6%) | 3 (42.9%) | 2 (40.0%) | 50 (40.3%) |
Three drug combinations | 10 (32.3%) | 10 (45.5%) | 0 | 2 (12.5%) | 0 | 1 (11.1%) | 1 (14.3%) | 2 (40.0%) | 26 (21.0%) |
Four and more drug combinations | 3 (9.7%) | 2 (9.1%) | 0 | 0 | 0 | 0 | 0 | 0 | 5 (4.0%) |
Number active agents | |||||||||
No active agent | 3 (9.7%) | 3 (13.6%) | 1 (5.6%) | 2 (12.5%) | 1 (6.3%) | 0 | 1 (14.3%) | 0 | 11 (8.9%) |
One active agent | 16 (51.6%) | 12 (54.5%) | 15 (83.3%) | 10 (62.5%) | 8 (50.0%) | 4 (44.4%) | 3 (42.9%) | 3 (60.0%) | 71 (57.3%) |
Two active agents | 9 (29.0%) | 4 (18.2%) | 1 (5.6%) | 3 (18.8%) | 3 (18.8%) | 4 (44.4%) | 1 (14.3%) | 2 (40.0%) | 27 (21.8%) |
Three active agents | 1 (3.2%) | 1 (4.5%) | 0 | 0 | 0 | 0 | 0 | 0 | 2 (1.6%) |
Four active agents | 0 | 1 (4.5%) | 0 | 0 | 0 | 0 | 0 | 0 | 1 (0.8%) |