Fig. 8

Different conformations exhibited by loop 1 (residues 1–9, in brown loop 2 (residues 43–53, denoted in olive green) and loop 3 (residues 82–92, represented in bottle green). Loop 1 and loop 2 remained semi-closed and closed in all the complexes, while the conformational changes were noticed with loop 3. The protein is represented in steel and the ligands in stick. The water molecule is denoted in blue and the Mg²⁺ ions in green