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Table 5 Predictors of Colistin nephrotoxicity

From: Comparison of nephrotoxicity of Colistin with Polymyxin B administered in currently recommended doses: a prospective study

Variable

Bivariate analysis

OR

95% CI

P value

BMI ≥ 30

0.92

0.31 to 2.73

0.885

DM (yes)

0.80

0.29 to 2.24

0.802

Age ≥ 65

1.64

0.58 to 4.65

0.350

Daily dose ≥ 300 mg/day

6.56

2.10 to 20.52

0.001

APACHE ≥ 20

0.39

0.13 to 1.11

0.387

Baseline creatinine clearance < 50 ml/min

0.16

0.05 to 0.53

0.003