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Table 1 Performance characteristics comparison of the developed qPCR method to those of the rapid antigen test (RAT) and the gold standard culture method for detection of GAS from the 687 throat swabs

From: Development of a fast and low-cost qPCR assay for diagnosis of acute gas pharyngitis

Results

Culture

RAT

QPCR

Positive

204

114

222

Negative

483

573

465

Prevalence

29.7 %

16.6 %

32.3 %

Sensitivity

 

69.4 %

100 %

Specificity

 

100 %

96.4 %

Positive predictive value

 

100 %

92.9 %

Negative predictive value

 

84.3 %

100 %