Table 2 Univariate analysis for primary outcome
Scale variables | Alive mean ± STD | Dead mean ± STD | 95 % CI | p value |
|---|---|---|---|---|
Age | 69 ± 17 | 75 ± 15 | 2 to 12 | 0.01 |
Charlson’s co-morbidity index | 4.8 ± 2.9 | 6.7 ± 2.5 | 0.8 to 2.5 | 0.0001 |
Temperature at the time of BSI | 38.3 ± 1 | 37.5 ± 1.4 | −1.2 to −0.4 | 0.0001 |
Mean arterial pressure at onset of GNBSI | 83 ± 17 | 73 ± 16 | −16 to −6 | 0.0001 |
Oxygen saturation at onset of GNBSI | 95.5 ± 3.4 | 93.9 ± 5.9 | −2.8 to −0.3 | 0.015 |
Glasgow coma scale | 14.7 ± 0.7 | 13.7 ± 1.8 | −1.5 to −0.5 | 0.0001 |
Sequential Organ Failure (SOFA) | 2.9 ± 2.3 | 5.8 ± 3.5 | 1.9 to 3.9 | 0.0001 |
EWS at the onset of GNBSI | 3.4 ± 2.2 | 5.6 ± 2.6 | 1.4 to 2.8 | 0.0001 |
C-reactive protein | 134 ± 104 | 190 ± 127 | 18 to 93 | 0.004 |
Serum bicarbonate | 23 ± 5 | 20 ± 5 | −3.6 to −0.6 | 0.007 |
Time interval-admission to GNBSI (days) | 6.4 ± 14 | 10 ± 14 | −0.7 to 7.8 | 0.1 |
Time interval-collection to positivity (h) | 1.6 ± 0.8 | 1.2 ± 0.6 | −0.5 to −0.1 | 0.001 |
Time to first antibiotic (h) | 18.7 ± 22.8 | 10.7 ± 17 | −13.8 to −2.3 | 0.006 |
Time to appropriate antibiotic (h) | 19.6 ± 24 | 14.6 ± 18 | −12.8 to 2.4 | 0.186 |
Time to source control (days) | 1.9 ± 2.1 | 0.64 ± 0.8 | −3.2 to 0.6 | 0.18 |
Categorical variable | Percentage | Percentage | p value | |
|---|---|---|---|---|
Gender: female/male | 79/76 | 21/24 | 0.5 | |
BSI onset: hospital/community | 64/85 | 36/15 | 0.0001 | |
BSI onset: out of h/routine h | 81/73 | 19/27 | 0.147 | |
Patient on oxygen/not on oxygen | 57/89 | 43/11 | 0.009 | |
On vasopressor/not on vasopressor | 46/79 | 54/21 | 0.009 | |
Polymicrobial BSI/monomicrobial BSI | 55/80 | 45/20 | 0.007 | |
ESBL positive/ESBL negative | 73/78 | 27/22 | 0.7 | |
Source of BSI: unknown/hepato-biliary | 65/90 | 35/10 | 0.033 |