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Table 3 Time kill results, expressed as average reduction of log10 of CFU/ml, of tigecycline against five A. baumannii strains with different susceptibilities to carbapenems.

From: In vitro activity of tigecycline and comparators against carbapenem-susceptible and resistant Acinetobacter baumannii clinical isolates in Italy

Concentration of tigecycline 2 h 4 h 8 h 24
MIC 0.6 × 10-1 3 × 10-2 3 × 10-2 3 × 10-2
2 × MIC 0.8 × 10-1 2.4 × 10-2 1.3 × 10-2 1.4 × 10-2
4 × MIC 1 × 10-1 1.4 × 10-2 1.2 × 10-2 1.2 × 10-2