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Table 1 viral signature analyses.

From: Predicting the sensitivity and specificity of published real-time PCR assays

Reference Number Scope Year Target Organism/gene True Positives False Positives False Negatives Sensitivity
[6] Strain 2004 Human coronavirus OC43 5 17 0 1.00
[6] Strain 2004 Human coronavirus 229E 1 0 0 1.00
[7] Strain 2004 Coxsackie virus B3 8 0 2 0.80
[8] Strain 2004 Coxsackie virus B4 3 78 0 1.00
[20] Serotype 2007 Influenza H5 strains 26 0 402 0.06
[21] Species 2004 Influenza A MP segment 238 0 3726 0.06
[21] Species 2004 Influenza B HA segment 131 0 238 0.36
[10] Species 2002 Dengue virus 0 0 185 0.00
[16] Serotype 2006 Dengue virus type 1 0 0 47 0.00
[16] Serotype 2006 Dengue virus type 2 0 0 57 0.00
[16] Serotype 2006 Dengue virus type 3 2 0 68 0.03
[16] Serotype 2006 Dengue virus type 4 0 0 11 0.00
[21] Species 2004 Adenovirus A 1 0 0 1.00
[21] Species 2004 Adenovirus B 17 0 3 0.85
[21] Species 2004 Adenovirus C 6 0 0 1.00
[21] Species 2004 Adenovirus D 6 0 0 1.00
[21] Species 2004 Adenovirus E 12 0 0 1.00
[21] Species 2004 Adenovirus F 2 0 0 1.00
[10] Species 2002 Lassa Virus 1 0 14 0.08
[9] Species 2004 Ebola Sudan 1 0 0 1.00
[9] Species 2004 Ebola Zaire 5 0 0 1.00
[9] Species 2004 Marburg Virus 13 0 5 0.72
[22] Species 1996 Hepatitis C virus 102 0 33 0.76
[10] Species 2002 Rift Valley fever virus 36 0 5 0.88
[23] Species 2000 West Nile Virus 3'NC 71 0 13 0.85
[23] Species 2000 West Nile Virus- ENV 71 0 13 0.85
[15] Species 2007 West Nile virus- RdRp 49 0 35 0.58
[15] Species 2007 Japanese encephalitis virus 0 0 43 0.00
[15] Species 2007 Yellow fever virus 0 0 15 0.00
[15] Species 2007 St. Louis encephalitis virus 0 0 2 0.00
[10] Species 2002 Yellow fever virus 10 0 5 0.67
[24] Species 2000 Hepatitis B virus (1) 942 0 56 0.94
[25] Species 2000 Hepatitis B virus (2) 641 0 357 0.64
[26] Species 2004 Cytomegalovirus 4 0 3 0.57
[21] Species 2004 Cytomegalovirus 4 0 3 0.57
[21] Species 2004 Epstein-Barr (HHV 4) 4 0 0 1.00
[27] Species 2005 Herpes Simplex Virus 1 1 0 0 1.00
[21] Species 2004 Herpes Simplex Virus 1 1 0 0 1.00
[27] Species 2005 Herpes Simplex Virus 2 1 0 0 1.00
[21] Species 2004 Herpes Simplex Virus 2 1 0 0 1.00
[28] Species 1999 Varicella-Zoster 19 0 0 1.00
[21] Species 2004 Varicella-Zoster 19 0 0 1.00
[21] Species 2004 Human herpesvirus 6 3 0 0 1.00
[21] Species 2004 Human herpesvirus 7 1 0 0 1.00
[21] Species 2004 Human herpesvirus 8 2 0 0 1.00
[29] Species 2005 Mumps virus 12 0 5 0.71
[30] Species 2004 Newcastle Disease irus 23 0 15 0.61
[21] Species 2004 Parainfluenzaviruses-1 1 0 0 1.00
[21] Species 2004 Parainfluenzaviruses-2 4 0 1 0.80
[21] Species 2004 Parainfluenzaviruses-3 2 0 0 1.00
[21] Species 2004 Respiratory syncytial virus 7 0 3 0.70
[21] Species 2004 Human parvovirus B19 3 0 0 1.00
[21] Genus 2004 Enteroviruses 170 0 21 0.89
[21] Species 2004 JC polyomavirus 378 0 2 1.00
[21] Species 2004 BK polyomavirus 120 378 0 1.00
[31] Species 2005 HIV – type 1 283 1 820 0.26
[10] Species 2002 Crimean-Congo hemorrhagic fever 27 0 21 0.56
[32] Genus 2001 Enterovirus genus 171 0 19 0.90
[10] Family 2002 Ebola and Marburg 6 0 21 0.22
  1. All but three are Taqman signatures. The three intercalating dye type assays are bolded.