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Table 1 Genotype analysis of 72 treatment naive HIV-positive patients with respect to baseline CD4 cell count and viral load.

From: No influence of the P-glycoprotein polymorphisms MDR1 G2677T/A and C3435T on the virological and immunological response in treatment naïve HIV-positive patients

CD4 [cells/μl]

VL [copies/μl]

n =

2677

3435

2677/3435$

   

GG

GT

TT

AG

AT

AA

CC

CT

TT

H1

H2

H3

H4

H5

<200

>105

27

7

7

8

3

2

-

7

10

10

5

15

2

-

5

 

104 – 105

8

4

3

1

-

-

-

2

6

-

2

4

2

-

-

 

<104

4

2

1

1

-

-

-

1

2

1

1

2

1

-

-

200

>105

6

2

3

1

-

-

-

1

4

1

1

4

1

-

-

-350

104 – 105

9

3

3

3

-

-

-

3

3

3

3

6

-

-

-

 

<104

1

1

-

-

-

-

-

1

-

-

1

-

-

-

-

>350

>105

7

1

4

2

-

-

-

1

3

3

1

6

-

-

-

 

104 – 105

7

1

2

2

1

1

-

2

4

1

1

4

-

-

2

 

<104

3

3

-

-

-

-

-

2

1

-

2

-

1

-

-

total

 

72

24

23

18

4

3

0

20

33

19

17

41

7

-

7

  1. $composite genotypes: H1: 2677GG and 3435CC (wild type); H2: 2677GT or TT and 3435CT or TT (2677T/3435T haplotype carrier); H3: 2677GG and 3435CT or TT; H4: 2677GT or TT and 3435CC; and H5: 2677AG or AT and any 3435 genotype (2677A carrier)
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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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