Table 4 Susceptibility of gram-negative organisms isolated from cerebrospinal fluid specimen sources. TSN Database USA 2000–2002
Organism | Antimicrobial | Total n | %Sa | %R |
|---|---|---|---|---|
Escherichia coli | amikacin | 164 | 98.8 | 0 |
ampicillin | 267 | 44.2 | 54.7 | |
aztreonam | 137 | 96.4 | 1.5 | |
cefotaxime | 168 | 98.2 | 0 | |
ceftazidime | 210 | 98.1 | 1.4 | |
ceftriaxone | 180 | 97.8 | 0.6 | |
gentamicin | 260 | 93.5 | 5.4 | |
levofloxacin | 198 | 97.5 | 2.5 | |
meropenem | 76 | 100 | 0 | |
piperacillin | 188 | 50.0 | 38.8 | |
TMP-SMXb | 252 | 77.0 | 23.0 | |
Pseudomonas aeruginosa | amikacin | 184 | 92.9 | 4.9 |
aztreonam | 133 | 67.7 | 15.0 | |
cefotaxime | 111 | 9.0 | 49.5 | |
ceftazidime | 236 | 80.1 | 11.0 | |
ceftriaxone | 116 | 6.0 | 61.2 | |
gentamicin | 251 | 80.9 | 11.2 | |
levofloxacin | 174 | 82.2 | 11.5 | |
meropenem | 97 | 84.5 | 10.3 | |
piperacillin | 198 | 82.8 | 17.2 | |
TMP-SMX | 128 | 0.8 | 99.2 | |
Enterobacter cloacae | amikacin | 160 | 98.8 | 0 |
ampicillin | 229 | 2.2 | 91.7 | |
aztreonam | 147 | 65.3 | 26.5 | |
cefotaxime | 154 | 63.6 | 28.6 | |
ceftazidime | 196 | 67.3 | 29.6 | |
ceftriaxone | 184 | 70.7 | 25.0 | |
gentamicin | 227 | 95.2 | 4.8 | |
levofloxacin | 176 | 96.0 | 4.0 | |
meropenem | 79 | 100 | 0 | |
piperacillin | 168 | 64.9 | 28.0 | |
TMP-SMX | 220 | 93.2 | 6.8 | |
Acinetobacter baumannii | amikacin | 112 | 75.0 | 17.9 |
aztreonam | 88 | 8.0 | 73.9 | |
cefotaxime | 102 | 21.6 | 54.9 | |
ceftazidime | 142 | 48.6 | 38.7 | |
ceftriaxone | 119 | 25.2 | 53.8 | |
gentamicin | 143 | 61.5 | 38.5 | |
levofloxacin | 106 | 53.8 | 43.4 | |
meropenem | 68 | 75.0 | 23.5 | |
piperacillin | 111 | 40.5 | 40.5 | |
TMP-SMX | 140 | 54.3 | 45.7 | |
Klebsiella pneumoniae | amikacin | 95 | 92.6 | 0 |
ampicillin | 129 | 0 | 98.4 | |
aztreonam | 70 | 84.3 | 14.3 | |
cefotaxime | 94 | 87.2 | 3.2 | |
ceftazidime | 111 | 76.6 | 18.0 | |
ceftriaxone | 108 | 84.3 | 2.8 | |
gentamicin | 131 | 87.8 | 8.4 | |
levofloxacin | 98 | 88.8 | 9.2 | |
meropenem | 47 | 100 | 0 | |
piperacillin | 102 | 65.7 | 26.5 | |
TMP-SMX | 133 | 83.5 | 16.5 | |
Serratia marcescens | amikacin | 71 | 95.8 | 2.8 |
ampicillin | 104 | 5.8 | 92.3 | |
aztreonam | 55 | 87.3 | 7.3 | |
cefotaxime | 70 | 80.0 | 8.6 | |
ceftazidime | 86 | 93.0 | 4.7 | |
ceftriaxone | 71 | 91.5 | 5.6 | |
gentamicin | 108 | 95.4 | 2.8 | |
levofloxacin | 80 | 98.8 | 1.3 | |
meropenem | 43 | 100 | 0 | |
piperacillin | 81 | 72.8 | 21.0 | |
TMP-SMX | 105 | 95.2 | 4.8 | |
Enterobacter aerogenes | amikacin | 60 | 100 | 0 |
ampicillin | 87 | 5.7 | 87.4 | |
aztreonam | 42 | 73.8 | 11.9 | |
cefotaxime | 54 | 74.1 | 1.9 | |
ceftazidime | 78 | 73.1 | 17.9 | |
ceftriaxone | 63 | 84.1 | 1.6 | |
gentamicin | 81 | 100 | 0 | |
levofloxacin | 51 | 100 | 0 | |
meropenem | 22 | 100 | 0 | |
piperacillin | 64 | 68.8 | 14.1 | |
TMP-SMX | 85 | 100 | 0 | |
Haemophilus influenzae | ampicillin | 61 | 72.1 | 24.6 |
cefotaxime | 27 | 100 | -d | |
ceftazidime | NAc | NA | NA | |
ceftriaxone | 54 | 100 | - | |
levofloxacin | 10 | 100 | - | |
TMP-SMX | 32 | 87.5 | 9.4 | |
Klebsiella oxytoca | amikacin | 37 | 100 | 0 |
ampicillin | 52 | 3.8 | 86.5 | |
aztreonam | 34 | 76.5 | 17.6 | |
cefotaxime | 37 | 81.1 | 16.2 | |
ceftazidime | 44 | 81.8 | 18.2 | |
ceftriaxone | 45 | 84.4 | 13.3 | |
gentamicin | 51 | 96.1 | 3.9 | |
levofloxacin | 39 | 100 | 0 | |
meropenem | 23 | 100 | 0 | |
piperacillin | 38 | 73.7 | 21.1 | |
TMP-SMX | 51 | 80.4 | 19.6 |