Table 1 Clinical characteristics of patients with ALF on admission and outcomes
Parameters | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Patient 8 | Patient 9 | Patient 10 | Patient 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|
Sex | male | male | male | male | male | female | male | male | male | male | male |
Outcome | death | survive | death | death | survive | survive | death | survive | death | death | death |
Age (years) | 70 | 27 | 28 | 58 | 50 | 55 | 44 | 26 | 39 | 47 | 47 |
Body Mass Index (kg/m2) | 26.12 | 23.94 | 24.49 | 23.25 | 27.44 | 22.15 | 24.34 | 26.23 | 22.02 | 24.62 | 27.18 |
Grade of HE | 4 | 2 | 3 | 3 | 1 | 3 | 3 | 1 | 3 | 4 | 3 |
Days from onset of illness to outcome (death or recovery) | 16 | 10 | 4 | 3 | 14 | 20 | 10 | 11 | 7 | 4 | 10 |
Serum ALT (U/L) | 1303 | 2000 | 4679 | 2917 | 941 | 1333 | 1645 | 3562 | 1164 | 1886 | 8294 |
Serum AST (U/L) | 664 | 1700 | 5111 | 3975 | 758 | 447 | 922 | 2277 | 516 | 155 | 6486 |
Serum TBil (μmol/L) | 225.2 | 463.1 | 173.5 | 180.6 | 386.3 | 173.6 | 216.0 | 179.0 | 194.2 | 173.9 | 215.0 |
Serum ALP (U/L) | 183 | 144 | 129 | 217 | 175 | 159 | 222 | 164 | 202 | 144 | 266 |
Serum LDH (U/L) | 230 | 138 | 1015 | 334 | 324 | 391 | 233 | 354 | 212 | 330 | 608 |
Serum Albumin (g/L) | 33 | 32 | 31 | 35 | 28 | 25 | 28 | 40 | 37 | 29 | 38 |
Serum glucose (mmol/L) | 7.6 | 2.5 | 12.1 | 17.5 | 2.3 | 3.8 | 11.0 | 4.8 | 3.1 | 10.5 | 4.3 |
Serum creatinine (μmol/L) | 117 | 58 | 97 | 168 | 118 | 69 | 95 | 68 | 77 | 90 | 92 |
Serum UN (mmol/L) | 4.8 | 3.3 | 3.0 | 1.9 | 6.1 | 2.5 | 1.8 | 1.5 | 4.3 | 1.7 | 2.7 |
Serum Na+ (mmol/L) | 135 | 138 | 137 | 133 | 135 | 139 | 133 | 140 | 137 | 137 | 132 |
Serum K+ (mmol/L) | 4.5 | 3.8 | 3.8 | 4.8 | 4.5 | 3.0 | 3.9 | 3.8 | 3.8 | 4.2 | 4.0 |
Serum Cl− (mmol/L) | 103.1 | 105.8 | 103.2 | 103.9 | 98.6 | 106.5 | 106.0 | 102.7 | 101.3 | 108.6 | 95.7 |
Serum HBV DNA (IU/mL) | 5.02 × 104 | 1.00 × 103 | 6.32 × 108 | 3.23 × 104 | 2.63 × 105 | 1.27 × 104 | 3.22 × 107 | 2.19 × 105 | 6.20 × 109 | 1.49 × 103 | 1.54 × 103 |
White blood cell count (×109) | 4.06 | 3.24 | 9.62 | 12.16 | 7.3 | 5.31 | 6.11 | 6.7 | 11.89 | 12.47 | 11.17 |
Platelet count (×109) | 149 | 122 | 87 | 88 | 97 | 44 | 66 | 147 | 120 | 29 | 38 |
Hemoglobin | 129 | 103 | 138 | 144 | 137 | 105 | 127 | 151 | 138 | 140 | 148 |
PTA (%) | 34 | 30 | 11 | 6.68 | 21.4 | 21.1 | 20 | 33 | 19.8 | 21 | 15 |
INR | 1.60 | 1.92 | 3.53 | 5.49 | 2.52 | 2.39 | 2.77 | 1.63 | 2.40 | 2.45 | 2.89 |
Arterial BLA (μmol/L) | 84 | 71 | 102 | 217 | 52 | 69 | 118 | 67 | 64 | 173 | 273 |