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Figure 1 | Annals of Clinical Microbiology and Antimicrobials

Figure 1

From: Intracellular activity of tedizolid phosphate and ACH-702 versus Mycobacterium tuberculosis infected macrophages

Figure 1

THP-1 cells infected with Mycobacterium tuberculosis H37Rv to a M.O.I.: 1:10 (cells:bacilli) were subjected to several concentrations of drugs in solution (0.25X and 1X MICs) and nanoparticles (0.25X, 1X, 4X and 16X MICs) in triplicate as described. After 72 h post infection, cells were lysed and plated on 7H10 to determine CFU/ml. Plots detail the bactericidal activity of ACH-702, Tedizolid, Moxifloxacin and Rifampicin. Values represent means ±1 standard error of the means.

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