Figure 2From: In vitro antifungal activity of farnesyltransferase inhibitors against clinical isolates of Aspergillus and CandidaRepresentative effect of manumycin A on the growth of Aspergillus fumigatus . 2 × 105 conidia of A. fumigatus-1 in 200 μl suspension were spread uniformly onto minimal medium agar plate. A 6-mm-diameter paper disk impregnated with 10 μl (20 mM) manumycin A was placed onto the center of the inoculated agar plate. The plate was then incubated at 35°C, and the diameter of the zone of inhibition was measured at 48 h.Back to article page