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Table 1 Minimum inhibitory concentrations of Nu-3 (mg/ml) and antibiotic controls (μg/ml) (ciprofloxacin, oxacillin and vancomycin).

From: Antimicrobial activity and mechanism of action of Nu-3, a protonated modified nucleotide

 

MIC

Strains

Nu-3 (mg/ml)

Ciprofloxacin (μg/ml)

Oxacillin (μg/ml)

Vancomycin (μg/ml)

Brucella abortus

>2.2

1

-

-

Burkholderia mallei

>4.4

1

-

-

Burkholderia pseudomallei

4.4

1

-

-

Bacillus anthracis (Sterne)

2.2

0.08

-

-

Francisella tularensis

2.2

0.08

-

-

Yersinia pestis

4.4

0.16

-

-

Staphylococcus aureus cvcc 2248

4.4

8

-

-

Pseudomonas aeruginosa cvcc 5668

8.8

4

-

-

MSSA ATCC 29213

8.8

-

0.4

1

MRSA ATCC 33591

>4.4

-

256

2

S. aureus ATCC 700699 GISA

8.8

-

>32

32

Stanford University MRSA Clinical Isolate #1

>4.4

-

256

2

Stanford University MRSA Clinical Isolate #2

8.8

-

128

1

Stanford University MRSA Clinical Isolate #3

8.8

-

>256

4

Stanford University MRSA Clinical Isolate #4

8.8

-

32

1

Stanford University MRSA Clinical Isolate #5

8.8

-

32

1

  1. MRSA: meticillin-resistant Staphylococcus aureus.