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Table 1 Minimum inhibitory concentrations of Nu-3 (mg/ml) and antibiotic controls (μg/ml) (ciprofloxacin, oxacillin and vancomycin).

From: Antimicrobial activity and mechanism of action of Nu-3, a protonated modified nucleotide

  MIC
Strains Nu-3 (mg/ml) Ciprofloxacin (μg/ml) Oxacillin (μg/ml) Vancomycin (μg/ml)
Brucella abortus >2.2 1 - -
Burkholderia mallei >4.4 1 - -
Burkholderia pseudomallei 4.4 1 - -
Bacillus anthracis (Sterne) 2.2 0.08 - -
Francisella tularensis 2.2 0.08 - -
Yersinia pestis 4.4 0.16 - -
Staphylococcus aureus cvcc 2248 4.4 8 - -
Pseudomonas aeruginosa cvcc 5668 8.8 4 - -
MSSA ATCC 29213 8.8 - 0.4 1
MRSA ATCC 33591 >4.4 - 256 2
S. aureus ATCC 700699 GISA 8.8 - >32 32
Stanford University MRSA Clinical Isolate #1 >4.4 - 256 2
Stanford University MRSA Clinical Isolate #2 8.8 - 128 1
Stanford University MRSA Clinical Isolate #3 8.8 - >256 4
Stanford University MRSA Clinical Isolate #4 8.8 - 32 1
Stanford University MRSA Clinical Isolate #5 8.8 - 32 1
  1. MRSA: meticillin-resistant Staphylococcus aureus.