Articles
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Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:41
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SARS-CoV-2/COVID-19 and advances in developing potential therapeutics and vaccines to counter this emerging pandemic
A novel coronavirus (SARS-CoV-2), causing an emerging coronavirus disease (COVID-19), first detected in Wuhan City, Hubei Province, China, which has taken a catastrophic turn with high toll rates in China and ...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:40 -
Majocchi’s granuloma on the forearm caused by Trichophyton tonsurans in an immunocompetent patient
Majocchi's granuloma is an uncommon fungal infection of the dermis and subcutaneous tissue. The most frequently identified cause of Majocchi’s granuloma is anthropophilic Trichophyton rubrum, and it is most commo...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:39 -
Nocardia takedensis: a newly recognized pathogen responsible for skin and soft tissue infections
Nocardia takedensis was first isolated in 2005, from soil in Japan. We report here two cases of lymphangitis in France (2012–2017) caused by N. takedensis both occurring after skin injury while gardening, which e...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:38 -
Safety and bactericidal efficacy of cold atmospheric plasma generated by a flexible surface Dielectric Barrier Discharge device against Pseudomonas aeruginosa in vitro and in vivo
Cold atmospheric plasma (CAP), which is ionized gas produced at atmospheric pressure, could be a novel and potent antimicrobial therapy for the treatment of infected wounds. Previously we have shown that CAP g...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:37 -
CTX-M-9 group ESBL-producing Raoultella planticola nosocomial infection: first report from sub-Saharan Africa
Raoultella are Gram-negative rod-shaped aerobic bacteria which grow in water and soil. They mostly cause nosocomial infections associated with surgical procedures. This case study is the first report of a Raoulte...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:36 -
The effect of an antibiotic stewardship program on tigecycline use in a Tertiary Care Hospital, an intervention study
A drug-oriented antibiotic stewardship intervention targeting tigecycline utilization was launched at Makassed General Hospital, Beirut, Lebanon, in 2016 as a part of a comprehensive Antibiotic Stewardship Pro...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:35 -
Prevention of cytomegalovirus infection after solid organ transplantation: a Bayesian network analysis
Cytomegalovirus infection is one of the most common complications after solid organ transplantation. There have been several classes of antiviral drugs for the prevention of cytomegalovirus infection, such as ...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:34 -
Nasal decolonization of Staphylococcus aureus and the risk of surgical site infection after surgery: a meta-analysis
To assess the effects of nasal decontamination on preventing surgical site infections (SSIs) in people who are Staphylococcus aureus carriers undergoing different types of surgeries and diverse measures of decolo...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:33 -
Complications of peritonsillar abscess
The vast majority of patients with peritonsillar abscess (PTA) recover uneventfully on abscess drainage and antibiotic therapy. However, occasionally patient´s condition deteriorates as the infection spread in...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:32 -
Case report on a swift shift in uropathogens from Shigella flexneri to Escherichia coli: a thin line between bacterial persistence and reinfection
Urinary tract infections (UTI) are mostly caused by bacteria. Urine cultures are usually a definitive measure to select the appropriate antibiotics for the elimination of a uropathogen and subsequent recovery ...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:31 -
Changes in the spatial distribution of COVID-19 incidence in Italy using GIS-based maps
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:30 -
In vitro estimation of superfluid critical extracts of some plants for their antimicrobial potential, phytochemistry, and GC–MS analyses
Along with swift economic evolution and continuous amelioration of lifestyle, people at present are paying more attention to health issues. Synthetic drugs will be compensated with other natural ones that belo...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:29 -
Hemophagocytic lymphohistiocytosis is associated with Bartonella henselae infection in a patient with multiple susceptibility genes
Adult-onset hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening condition, which is often triggered by certain types of infection, cancer and numerous autoimmune diseases; however, of the n...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:28 -
Nomogram to predict multidrug-resistant tuberculosis
Multidrug-resistant tuberculosis (MDR-TB) is burgeoning globally, and has been a serious challenge in TB management. Clinically, the ability to identify MDR-TB is still limited, especially in smear-negative TB...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:27 -
Coagulase-negative staphylococci (CoNS) as a significant etiological factor of laryngological infections: a review
This review article shows that coagulase-negative staphylococci (CoNS) are widely responsible for laryngological diseases. General characteristics of CoNS infections are shown in the introduction, and the path...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:26 -
Multi-drug resistant and extended-spectrum β-lactamases producing bacterial uropathogens among pregnant women in Northwest Ethiopia
Above 80% of urinary tract infections are caused by enteric bacteria, which are known for years by their drug-resistant ability. Though the prevalence of drug-resistant strains is increasing in the world, it i...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:25 -
Emerging high-risk ST101 and ST307 carbapenem-resistant Klebsiella pneumoniae clones from bloodstream infections in Southern Italy
Carbapenem-resistant Klebsiella pneumoniae (CR-KP) is an urgent public health issue in Italy. This pattern of resistance is due mainly to dissemination of carbapenemase genes. Molecular characterization of carbap...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:24 -
Ivermectin, a new candidate therapeutic against SARS-CoV-2/COVID-19
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:23 -
Presence of Borrelia miyamotoi infection in a highly endemic area of Lyme disease
A series of cases in the Northeast of the US during 2013–2015 described a new Borrelia species, Borrelia miyamotoi, which is transmitted by the same tick species that transmits Lyme disease and causes a relapsing...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:22 -
Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes
The COVID-19 pandemic has currently overtaken every other health issue throughout the world. There are numerous ways in which this will impact existing public health issues. Here we reflect on the interactions...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:21 -
New ST623 of Cryptococcus neoformans isolated from a patient with non-Hodgkin’s lymphoma in the Brazilian Amazon
Cryptococcosis is a disease of wide geographic distribution. It is most critical when it affects immunocompromised patients, with AIDS, tuberculosis or other diseases that require prolonged hospitalization.
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:20 -
Venezuelan equine encephalitis virus: the problem is not over for tropical America
The equine encephalitis viruses, Venezuelan (VEEV), East (EEEV) and West (WEEV), belong to the genus alphavirus, family Togaviridae and still represent a threat for human and animal public health in the Americ...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:19 -
Plasma CRP level is positively associated with the severity of COVID-19
The coronavirus disease 2019 (COVID-19) is characterized as highly contagious and deadly; however there is no credible and convenient biomarker to predict the severity of the disease. The aim of the present st...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:18 -
Characterisation of antibiotic resistance, virulence, clonality and mortality in MRSA and MSSA bloodstream infections at a tertiary-level hospital in Hungary: a 6-year retrospective study
Staphylococcus aureus bloodstream infections (BSI) cause significant morbidity and mortality due to the frequent antibiotic resistance, toxin and adhesin production of the bacterium. These characteristics differ ...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:17 -
Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin
COVID-19 pandemics is a challenge for public health and infectious diseases clinicians, especially for the therapeutical approach that is not yet adequately defined. Amid this situation, investigational agents...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:16 -
Microbiota composition and distribution along the female reproductive tract of women with endometriosis
Endometriosis (EMS) is a multifactorial disease that affects 10%–15% women of reproductive age and is associated with chronic pelvic pain and infertility. The pathogenesis of EMS has not been consistently expl...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:15 -
In vitro activity of ceftazidime–avibactam and comparators against Gram-negative bacterial isolates collected in the Asia–Pacific region as part of the INFORM program (2015–2017)
Antimicrobial resistance among nosocomial Gram-negative pathogens is a cause for concern in the Asia–Pacific region. The aims of this study were to measure the rates of resistance among clinical isolates colle...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:14 -
The risk of vancomycin toxicity in patients with liver impairment
The influence of liver disease on the pharmacokinetic profile, the risk of acute kidney injury, and excessive drug exposure in patients treated with vancomycin was examined.
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:13 -
The emergence of the hypervirulent Klebsiella pneumoniae (hvKp) strains among circulating clonal complex 147 (CC147) harbouring blaNDM/OXA-48 carbapenemases in a tertiary care center of Iran
Klebsiella pneumoniae is a public health concern because of its ability to develop multidrug resistance and hypervirulent genotypes, of those capsular types K1 and K2 cause community and nosocomial life-threateni...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:12 -
Comparison of fungal and bacterial keratitis between tropical and subtropical Taiwan: a prospective cohort study
Fungal keratitis (FK) has been shown to be a climate-sensitive disease. The differentiation between FK from bacterial keratitis (BK) was difficult. The purpose of this study was to compare the bacteriology and...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:11 -
Investigation of biofilm production and its association with genetic and phenotypic characteristics of OM (osteomyelitis) and non-OM orthopedic Staphylococcus aureus
Staphylococcus aureus is a primary pathogen of orthopedic infections. By mediating antimicrobial resistance, S. aureus biofilm plays an important role in the recalcitrance of orthopedic infections, especially for...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:10 -
Ceftobiprole: a potential empirical post-operative monotherapy in prosthetic joint infections
This study aimed to evaluate in vitro susceptibility to ceftobiprole of clinical strains identified from prosthetic joint infections (PJIs) compared to that of the associations currently recommended for post-o...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:9 -
A rapid and simple method for routine determination of antibiotic sensitivity to biofilm populations of Pseudomonas aeruginosa
Treatment of infections by Pseudomonas aeruginosa forming biofilms after antimicrobial testing on planktonic bacteria can result in substantial failure. Therefore, we offer a robust and simple experimental platfo...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:8 -
Antimicrobial utilization and antimicrobial resistance in patients with haematological malignancies in Japan: a multi-centre cross-sectional study
Infection is a major complication for patients with haematological malignancies. It is important to better understand the use of antimicrobial agents and antibiotic resistance for appropriate treatment and pre...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:7 -
Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review
Recurrent vulvovaginal infections (RVVI) has not only become an epidemiological and clinical problem but also include large social and psychological consequences. Understanding the mechanisms of both commensal...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:5 -
The challenging management of Rift Valley Fever in humans: literature review of the clinical disease and algorithm proposal
Rift Valley Fever (RVF) is an emerging zoonotic arbovirus with a complex cycle of transmission that makes difficult the prediction of its expansion. Recent outbreaks outside Africa have led to rediscover the h...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:4 -
Pharmacokinetics of plasma lopinavir and ritonavir in tuberculosis–HIV co-infected African adult patients also receiving rifabutin 150 or 300 mg three times per week
To evaluate the pharmacokinetic of plasma lopinavir (LPV) and ritonavir (RTV) when co-administered with three times weekly (TPW) rifabutin (RBT) at a dose of either 150 or 300 mg in African tuberculosis (TB) a...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:3 -
Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan
Acinetobacter baumannii is a Gram-negative opportunistic pathogen with a notorious reputation of being resistant to antimicrobial agents. The capability of A. baumannii to persist and disseminate between healthca...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:2 -
Klebsiella pneumoniae: an increasing threat to public health
This review fills the paucity of information on K. pneumoniae as a nosocomial pathogen by providing pooled data on epidemiological risk factors, resistant trends and profiles and resistant and virulent genes of t...
Citation: Annals of Clinical Microbiology and Antimicrobials 2020 19:1 -
Evolving trends in infective endocarditis in a developing country: a consequence of medical progress?
Staphylococcus has replaced streptococcus as the most common cause of infective endocarditis (IE) in developed health care systems. The trend in developing countries is less clear.
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:43 -
Extended spectrum β-lactamase producing uropathogenic Escherichia coli and the correlation of biofilm with antibiotics resistance in Nepal
Urinary tract infection (UTI) is one of the frequently diagnosed infectious diseases which is caused mainly by Escherichia coli. E. coli confers resistance against the two major classes of antibiotics due to the ...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:42 -
Molecular detection and antibiotic resistance pattern of extended-spectrum beta-lactamase producing Escherichia coli in a Tertiary Hospital in Enugu, Nigeria
The use of antibiotic agents in the treatment of infectious diseases has greatly contributed to the decrease in morbidity and mortality, but these great advances in treatment are being undermined by the rapidl...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:41 -
Emergence of colistin resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli strains isolated from cancer patients
Colistin resistance is mainly driven by alterations in the Gram-negative outer membrane lipopolysaccharides and is caused, in most cases, by mutations in mgrB gene. However, the recent emergence of plasmid-encode...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:40 -
Multiplex ligation reaction based on probe melting curve analysis: a pragmatic approach for the identification of 30 common Salmonella serovars
While Salmonella serotyping is of paramount importance for the disease intervention of salmonellosis, a fast and easy-to-operate molecular serotyping solution remains elusive. We have developed a multiplex ligati...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:39 -
Potential factors contributing to the poor antimicrobial efficacy of SAAP-148 in a rat wound infection model
We investigated the efficacy of a synthetic antimicrobial peptide SAAP-148, which was shown to be effective against Methicillin-resistant Staphylococcus aureus (MRSA) on tape-stripped mice skin. Unexpectedly, SAA...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:38 -
Determination of antimicrobial susceptibility and biofilm production in Staphylococcus aureus isolated from white coats of health university students
This study aimed at detecting Staphylococcus aureus from white coats of college students and characterizing antimicrobial susceptibility and biofilm production. Bacterial samples (n = 300) were obtained from whit...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:37 -
Systematic review of carbapenem-resistant Enterobacteriaceae causing neonatal sepsis in China
Carbapenems are β-lactam antibiotics which are used to treat severe infections caused by multidrug resistant Enterobacteriacea. The recent emergence and rapid spread of Enterobacteriaceae resistant to carbapenems...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:36 -
Effect of camera monitoring and feedback along with training on hospital infection rate in a neonatal intensive care unit
In terms of pediatric healthcare-associated infections (HAI), neonatal intensive care units (NICU) constitute the greatest risk. Contacting a health care personnel, either directly or indirectly, elevates NICU...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:35 -
Doxycycline-encapsulated solid lipid nanoparticles for the enhanced antibacterial potential to treat the chronic brucellosis and preventing its relapse: in vivo study
Brucellosis is one of the most important infection of diseases. Due to its large period of treatment and survival ability of bacteria inside the macrophages, relapse of this disease is the main challenge, espe...
Citation: Annals of Clinical Microbiology and Antimicrobials 2019 18:33