Fig. 5

Hierarchical clustering of the bacterial taxa in oral biofilm samples of three different groups of 179 study participants based on metagenomic sequencing; A PCoA clustering of the microbial composition resulting in three clusters defining three ecotypes; B percentages of samples from H, C, and P belonging to each ecotype. Healthy (n = 63, 60.3% female), Caries (n = 61, 31.1% female), and Periodontitis (n = 55, 41.8% female)