Table1 Characteristics of 357 Delta variant–infected patients with different vaccination statuses
Unvaccinated (n = 105) | Partially Vaccinated (n = 72) | Fully Vaccinated (n = 180) | P-value | |
|---|---|---|---|---|
Demographics and clinical characteristics | ||||
Sex | ||||
Male | 40 (38.1) | 35 (48.6) | 67 (37.2) | 0.233 |
Female | 65 (61.9) | 37 (51.4) | 113 (62.8) | |
Age, years | 67.00 [52.00, 74.00] | 51.00 [39.75, 67.25] | 44.00 [37.00, 52.00] | < 0.001 |
18–59 | 36 (34.3) | 46 (63.9) | 167 (92.8) | < 0.001 |
≥ 60 | 69 (65.7) | 26 (36.1) | 13 (7.2) | |
With any comorbidity | 45 (42.9) | 23 (31.9) | 33 (18.3) | < 0.001 |
Hypertension | 34 (32.4) | 18 (25.0) | 23 (12.8) | < 0.001 |
Diabetes | 13 (12.4) | 7 (9.7) | 9 (5.0) | 0.069 |
Heart disease | 7 (6.7) | 2 (2.8) | 2 (1.1) | 0.029 |
Tumor | 6 (5.7) | 1 (1.4) | 1 (0.6) | 0.013 |
Asthma | 4 (3.8) | 0 (0.0) | 2 (1.1) | 0.143 |
Autoimmune diseases | 1 (1.0) | 1 (1.4) | 2 (1.1) | 1.000 |
Time from illness onset to hospitalization | 3.00 [2.00, 5.00] | 3.00 [1.00, 4.00] | 2.00 [1.00, 4.00] | 0.004 |
Symptoms | ||||
Fever | 38 (36.2) | 26 (36.1) | 48 (26.7) | 0.148 |
Cough | 50 (47.6) | 35 (48.6) | 94 (52.2) | 0.743 |
Shortness of breath | 7 (6.7) | 3 (4.2) | 2 (1.1) | 0.029 |
Loss of smell or taste | 2 (1.9) | 2 (2.8) | 11 (6.1) | 0.212 |
Stuffy nose or runny nose | 9 (8.6) | 9 (12.5) | 32 (17.8) | 0.088 |
Pharyngeal discomfort | 21 (20.0) | 20 (27.8) | 41 (22.8) | 0.464 |
Blood laboratory findings | ||||
C-reactive protein-mg/L | 4.89 [0.50, 12.01] | 6.77 [2.46, 20.12] | 5.72 [2.20, 14.24] | 0.177 |
> 10 | 31 (29.5) | 32 (44.4) | 63 (35.0) | 0.126 |
Interleukin-6, pg/mL | 16.93 [8.73, 28.58] | 15.97 [4.77, 25.06] | 5.92 [1.50, 13.57] | < 0.001 |
> 7 | 84 (80.8) | 51 (71.8) | 77 (43.0) | < 0.001 |
Lymphocyte count, × 109/L | 1.07 [0.90, 1.44] | 1.29 [0.90, 1.69] | 1.17 [0.88, 1.56] | 0.210 |
< 0.8 | 21 (20.0) | 14 (19.4) | 28 (15.6) | 0.560 |
LDH, IU/L | 245.00 [214.00, 292.00] | 244.50 [203.50, 282.75] | 230.5 [197.75, 269.25] | 0.068 |
> 245 | 52 (49.5) | 36 (50.0) | 72 (40.0) | 0.186 |
D-dimer, mg/L | 0.40 [0.27, 0.64] | 0.41 [0.28, 0.62] | 0.35 [0.21, 0.58] | 0.083 |
> 0.55 | 35 (33.3) | 21 (29.2) | 48 (26.7) | 0.481 |
Microbiological and serological data | ||||
SARS-COV-2 IgM, S/CO | 0.06 [0.03, 0.31] | 0.37 [0.08, 1.26] | 0.34 [0.11, 1.24] | < 0.001 |
IgM positive | 16 (15.2) | 20 (27.8) | 55 (30.6) | 0.012 |
SARS-COV-2 IgG (S/CO) | 0.10 [0.05, 0.26] | 0.52 [0.15, 2.24] | 5.56 [2.35, 34.87] | < 0.001 |
IgG Positive | 14 (13.3) | 28 (38.9) | 152 (84.4) | < 0.001 |
Viral load (Ct value) | ||||
ORF1ab gene | 23.00 [20.00, 27.00] | 24.50 [20.00, 29.00] | 22.00 [19.00, 27.00] | 0.179 |
N gene | 20.00 [17.00, 24.00] | 20.50 [16.75, 26.00] | 19.50 [15.00, 24.00] | 0.166 |