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Table 5 WGS predictions versus DST phenotype for BDQ

From: Investigation of bedaquiline resistance and genetic mutations in multi-drug resistant Mycobacterium tuberculosis clinical isolates in Chongqing, China

WGS

DST phenotype (n)

Total

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Kappa

Resistant(9)

Sensitive(196)

Mutation

6

2

8

66.7(30.9–91.0)

99.0(96.0–99.8)

75.0(35.6–95.5)

98.5(95.3–99.6)

0.693

Non-mutaion

3

194

197