Patient | Total n = 38 (%) | Survivors at 30 d, n = 32 (%) | Death within 30 d, n = 3 (%) | p value | Survivors at 90 d, n = 23 (%) | Death within 90 d, n = 8 (%) | p value |
---|---|---|---|---|---|---|---|
Age (median) [range] | 77.5 (25–98) | 76.5 (25–92) | 83 (79–85) | 0.111 | 75 (25–87) | 79 (70–90) | 0.13 |
Sex, no. of patients | |||||||
Male | 22 (57.9) | 19 (59.4) | 2 (66.7) | 1.00 | 13 (56.5) | 6 (75.0) | 0.433 |
Female | 16 (42.1) | 13 (40.6) | 1 (33.3) | 10 (43.5) | 2 (25.0) | ||
Symptoms, no. of patients | |||||||
Fever (≥ 37.5 °C) | 26 (68.4) | 22 (68.8) | 2 (66.7) | 1.00 | 14 (60.9) | 7 (87.5) | 0.222 |
Appetite loss | 17 (44.7) | 12 (37.5) | 3 (100) | 0.069 | 7 (30.4) | 6 (75.0) | 0.043 |
Nausea/vomiting | 6 (15.8) | 6 (18.6) | 0 (0) | 1.00 | 4 (17.4) | 0 (0) | 0.55 |
Proceeded diarrhea | 1 (2.6) | 1 (3.1) | 0 (0) | 1.00 | 0 (0) | 1 (12.5) | 0.258 |
Sepsis | 9 (23.7) | 8 (25.0) | 1 (33.3) | 1.00 | 2 (8.7) | 5 (62.5) | 0.006 |
Underlying disease* | |||||||
Solid tumor | |||||||
Hepatobiliary or pancreatic cancer | 12 (31.6) | 9 (28.1) | 2 (66.7) | 0.227 | 5 (21.7) | 5 (62.5) | 0.074 |
Gastrointestinal cancer | 6 (15.8) | 5 (15.6) | 1 (33.3) | 0.442 | 3 (13.0) | 2 (25.0) | 0.583 |
Lung cancer | 4 (10.5) | 4 (12.5) | 0 (0) | 1.00 | 3 (13.0) | 1 (12.5) | 1.00 |
Prostate cancer | 2 (5.3) | 2 (6.3) | 0 (0) | 1.00 | 2 (8.7) | 0 (0) | 1.00 |
Laryngeal cancer | 3 (7.9) | 3 (9.4) | 0 (0) | 1.00 | 3 (13.0) | 0 (0) | 0.55 |
Hematologic malignancy | 1 (2.6) | 1 (3.1) | 0 (0) | 1.00 | 1 (4.3) | 0 (0) | 1.00 |
Receipt of anticancer chemotherapy | 11 (28.9) | 10 (31.2) | 1 (33.3) | 1.00 | 6 (26.1) | 2 (25.0) | 0.676 |
Receiving palliative care | 6 (15.8) | 3 (9.4) | 2 (66.7) | 0.047 | 0 (0) | 5 (62.5) | 0.0003 |
Metastatic tumor | 6 (15.8) | 5 (15.6) | 1 (33.3) | 0.442 | 2 (8.7) | 4 (50.0) | 0.026 |
Bile duct stent or drainage tube placement | 8 (21.1) | 5 (15.6) | 2 (66.7) | 0.095 | 4 (17.4) | 3 (37.5) | 0.335 |
Diabetes mellitus | 10 (26.3) | 10 (31.3) | 0 (0) | 0.542 | 8 (34.8) | 2 (25.0) | 1.00 |
Hypertension | 18 (47.4) | 16 (50.0) | 1 (33.3) | 1.00 | 11 (47.8) | 4 (50.0) | 1.00 |
Cardiovascular disease | 4 (10.5) | 3 (9.4) | 0 (0) | 1.00 | 3 (13.0) | 0 (0) | 0.55 |
Gallstone | 17 (44.7) | 14 (43.8) | 0 (0) | 0.259 | 12 (52.2) | 1 (12.5) | 0.095 |
Chronic liver disease** | 4 (10.5) | 4 (12.5) | 0 (0) | 1.00 | 3 (13.0) | 0 (0) | 0.55 |
Chronic lung disease*** | 7 (18.4) | 6 (18.6) | 0 (0) | 1.00 | 6 (26.1) | 0 (0) | 0.298 |
Chronic kidney disease**** | 3 (7.9) | 2 (6.3) | 0 (0) | 1.00 | 2 (8.7) | 0 (0) | 1.00 |
Dementia | 3 (7.9) | 1 (3.1) | 1 (33.3) | 0.166 | 0 (0) | 2 (25.0) | 0.060 |
Stroke | 7 (18.4) | 6 (18.6) | 0 (0) | 1.00 | 2 (8.7) | 2 (25.0) | 0.268 |
Receipt of any immunosuppressant***** | 2 (5.3) | 2 (6.3) | 0 (0) | 1.00 | 2 (8.7) | 0 (0) | 1.00 |
Connective tissue disease | 1 (2.6) | 1 (3.1) | 0 (0) | 1.00 | 1 (4.3) | 0 (0) | 1.00 |
Charlson comorbidity index (median) (range) | 5 (0–11) | 5 (0–11) | 7 (5–10) | 0.189 | 5 (1–11) | 8.5 (5–10) | 0.002 |
Types of bacteremia | |||||||
Monomicrobial bacteremia | 22 (57.9) | 19 (59.4) | 1 (33.3) | 0.565 | 14 (60.9) | 3 (37.5) | 0.412 |
Polymicrobial bacteremia | 16 (42.1) | 13 (40.6) | 2 (66.7) | 0.565 | 9 (39.1) | 5 (62.5) | 0.412 |
Source of bacteremia | |||||||
Hepatobiliary | |||||||
Cholangitis | 21 (55.7) | 17 (53.1) | 2 (66.7) | 1.00 | 11 (47.8) | 5 (62.5) | 0.685 |
Cholecystitis | 7 (18.4) | 5 (15.6) | 0 (0) | 1.00 | 4 (17.4) | 0 (0) | 0.55 |
Liver abscess | 4 (10.5) | 4 (12.5) | 0 (0) | 1.00 | 4 (17.4) | 0 (0) | 0.55 |
Gynecologic | 2 (5.2) | 2 (5.7) | 0 | 1.00 | 1 (4.3) | 0 (0) | 1.00 |
Intraabdominal abscess | 3 (7.9) | 2 (5.7) | 1 (33.3) | 0.242 | 0 (0) | 2 (25.0) | 0.013 |
Appendicitis | 1 (2.6) | 1 (3.1) | 0 (0) | 1.00 | 0 (0) | 0 (0) | 1.00 |
Spontaneous bacterial peritonitis | 1 (2.6) | 1 (3.1) | 0 (0) | 1.00 | 0 (0) | 0 (0) | 0.258 |
Febrile neutropenia | 1 (2.6) | 1 (3.1) | 0 (0) | 1.00 | 1 (4.3) | 0 (0) | 0.258 |
Unknown | 1 (2.6) | 1 (3.1) | 0 (0) | 1.00 | 0 (0) | 1 (12.5) | 0.258 |