Skip to main content

Table 4 Effects of antibiotic exposure during the first one year of life on the compositions of gut microbiota at the two and a half years

From: Early-life antibiotic exposure increases the risk of childhood overweight and obesity in relation to dysbiosis of gut microbiota: a birth cohort study

Gut microbiota (%)*

Control group

(n = 60)

Antibiotic exposed group (n = 60)

t/Z

P

Firmicutes

59.39 ± 2.34

64.85 ± 2.49

1.597

0.113

unidentified_Lachnospiraceae

10.25 ± 1.35

9.56 ± 1.15

0.391

0.697

Faecalibacterium

5.57 ± 0.98

9.20 ± 1.31

2.226

0.028

Blautia

7.79 ± 0.89

6.89 ± 0.61

0.862

0.390

Agathobacter

2.65 ± 0.61

5.51 ± 1.27

2.028

0.046

Streptococcus&

5.65 ± 1.18

5.22 ± 0.87

0.301

0.765

Subdoligranulum-i

3.23 ± 0.56

4.77 ± 0.87

1.493

0.138

Erysipelatoclostridium

4.41 ± 0.80

3.06 ± 0.48

1.449

0.151

unidentified_Ruminococcaceae

2.73 ± 0.64

2.07 ± 0.38

0.917

0.361

Fusicatenibacter&

1.58 ± 0.24

1.74 ± 0.29

0.398

0.691

Dialister

1.05 ± 0.41

1.73 ± 0.54

0.976

0.331

Anaerostipes

1.22 ± 0.19

1.69 ± 0.33

1.259

0.211

unidentified_Erysipelotrichaceae

2.18 ± 0.64

1.60 ± 0.28

0.831

0.409

Lachnospira

0.71 ± 0.27

1.25 ± 0.44

1.004

0.318

Holdemanella

0.51 ± 0.38

0.35 ± 0.21

0.361

0.719

Actinobacteria&

27.93 ± 2.63

22.13 ± 2.29

1.666

0.099

Bifidobacterium &

26.79 ± 2.57

20.87 ± 2.13

2.032

0.045

Proteobacteria

5.25 ± 0.84

8.71 ± 1.85

1.705

0.092

unidentified_Enterobacteriaceae

3.52 ± 0.70

3.94 ± 0.93

0.351

0.726

Klebsiella

0.72 ± 0.19

2.37 ± 0.84

2.016

0.050

Citrobacter

0.23 ± 0.054

0.77 ± 0.32

1.626

0.109

Bacteroidetes

5.17 ± 1.05

3.63 ± 0.66

1.284

0.202

Bacteroides

4.57 ± 0.95

3.13 ± 0.62

1.262

0.210

Verrucomicrobia

2.20 ± 0.81

0.62 ± 0.34

1.814

0.074

Akkermansia&

2.20 ± 0.81

0.62 ± 0.34

1.813

0.074

Tenericutes

0.011 ± 0.0067

0.017 ± 0.0091

0.489

0.626

unidentified_Bacteria

0.021 ± 0.0041

0.015 ± 0.0033

1.301

0.196

Fusobacteria&

0.0071 ± 0.0019

0.0091 ± 0.0029

0.549

0.584

Cyanobacteria

0.0069 ± 0.0025

0.0044 ± 0.0012

0.950

0.344

Synergistetes

0.00086 ± 0.00060

0.0013 ± 0.00074

0.414

0.680

Others

0.0091 ± 0.0017

0.011 ± 0.0037

0.447

0.656

  1. Note: *The compositions of gut microbiota at the phylum and genus levels were shown as mean ± standard error (SE), in which Mann-Whitney U test was used to evaluate the percentages of gut microbiota (&) under the non-normal distribution, while the other variables were analyzed by t test, in which the data with statistically significant differences were shown in bold.