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Table 2 Effects of antibiotic exposure in the first one year of life on the growth and development outcomes from birth to two and a half years old

From: Early-life antibiotic exposure increases the risk of childhood overweight and obesity in relation to dysbiosis of gut microbiota: a birth cohort study

Variables*

Control group

(n = 1005)

Antibiotic exposed group (n = 1135)

t/χ2

P

At birth

Height (cm)

50.09 ± 1.71

50.08 ± 1.69

0.142

0.887

Weight (kg)

3.32 ± 0.44

3.38 ± 0.47

1.164

0.246

BMI (kg/m2)

13.23 ± 1.52

13.47 ± 1.61

0.611

0.541

Six months

Height (cm)

68.57 ± 2.56

68.99 ± 2.85

1.209

0.228

Weight (kg)

8.25 ± 1.38

8.64 ± 1.21

1.624

0.106

BMI (kg/m2)

17.54 ± 2.52

18.15 ± 1.89

1.658

0.099

One year

Height (cm)

76.32 ± 2.58

76.54 ± 2.84

1.192

0.234

Weight (kg)

9.79 ± 1.06

10.11 ± 1.24

1.201

0.230

BMI (kg/m 2 )

16.78 ± 1.27

17.23 ± 1.50

4.547

< 0.001

Overweight (n, %)

106 (10.55)

154 (13.57)

4.558

0.033

Obesity (n, %)

31 (3.08)

56 (4.93)

4.674

0.031

One and a half years

Height (cm)

82.89 ± 2.81

83.13 ± 2.86

1.437

0.151

Weight (kg)

11.00 ± 1.12

11.61 ± 1.27

2.328

0.020

BMI (kg/m 2 )

16.01 ± 1.15

16.80 ± 1.28

10.718

< 0.001

Overweight (n, %)

98 (9.75)

144 (12.69)

4.581

0.032

Obesity (n, %)

24 (2.39)

52 (4.58)

7.487

0.006

Two years

Height (cm)

88.26 ± 3.15

88.09 ± 3.08

0.962

0.338

Weight (kg)

12.56 ± 1.38

12.74 ± 1.45

1.495

0.135

BMI (kg/m 2 )

16.12 ± 1.48

16.52 ± 1.58

2.868

0.004

Overweight (n, %)

114 (11.34)

181 (15.95)

9.506

0.002

Obesity (n, %)

41 (4.08)

74 (6.52)

6.242

0.012

Two and a half years

Height (cm)

92.77 ± 3.40

93.53 ± 3.33

1.454

0.147

Weight (kg)

13.40 ± 1.42

14.31 ± 1.54

7.547

< 0.001

BMI (kg/m 2 )

15.57 ± 1.13

16.32 ± 1.12

8.507

< 0.001

Overweight (n, %)

122 (12.14)

193 (17.01)

10.050

0.002

Obesity (n, %)

44 (4.38)

71 (6.26)

4.130

0.043

  1. Note: * The prevalence of overweight and obesity was shown as n (%) and analyzed by χ2 test between the control and antibiotic exposed groups, while the other variables were shown as mean ± standard deviation (SD) and analyzed by t test, in which the data with statistically significant differences were shown in bold.