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Table 2 Interpretive criteria and MIC values of CCM, CAP and antimicrobial agents tested against C. difficile strains

From: Curcumin and capsaicin regulate apoptosis and alleviate intestinal inflammation induced by Clostridioides difficile in vitro

Agents

Interpretation

MIC

S

I

R

RT 001

RT 126

RT 084

700057

CCM (μM)

–

–

–

256

256

128

128

CAP (μM)

–

–

–

256

256

128

128

MET (μg/ml)

 ≤ 8

16

 ≥ 32

1

0.5

0.5

0.5

VAN (μg/ml)

 ≤ 2

NA

 ≥ 8

0.5

0.5

1

0.5

FDX (μg/ml)

 ≤ 1

 > 1

NA

0.5

0.5

0.5

0.5

  1. Breakpoints were defined as susceptible (S), intermediately resistant (I), or resistant (R) with reference to CLSI, EUCAST or published data. NA, not available
  2. CCM curcumin, CAP capsaicin, MET metronidazole, VAN vancomycin, FDX fidaxomicin