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Fig. 1 | Annals of Clinical Microbiology and Antimicrobials

Fig. 1

From: A novel antibiotic combination of linezolid and polymyxin B octapeptide PBOP against clinical Pseudomonas aeruginosa strains

Fig. 1

Treatment of LP reduced bacterial burdens. A1–A4 1 × 105 CFU of PA14 were seeded in 96-well plates and treated with PBS, linezolid, PBOP or combination of linezolid and PBOP (LP) for 1 h (A1), 6 h (A2), 12 h (A3), and 24 h (A4). The bacteria burdens on the LB agar plates were counted. B1–B4 1 × 105 CFU of PA2 were seeded in 96-well plates and treated with PBS, linezolid, PBOP or LP for 1 h (B1), 6 h (B2), 12 h (B3), and 24 h (B4). C1–C4 1 × 105 CFU of PAB41 were seeded in 96-well plates and treated with PBS, linezolid, PBOP or LP for 1 h (C1), 6 h (C2), 12 h (C3), and 24 h (C4). The bacteria burdens were determined as described above. Data are shown as the mean ± SEM of three independent experiments. ***p < 0.001, **p < 0.01

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