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Table 2 Fractional inhibitory concentration index (FICI) of terbinafine and tested antibiotics against S. aureus ATCC 6538

From: Antibiofilm and staphyloxanthin inhibitory potential of terbinafine against Staphylococcus aureus: in vitro and in vivo studies

Agent

MIC (µg∕mL)

FIC

FICI

Interpretation

Alone

Combination

Terbinafine

2624

20.5

0.08

0.14

S

Ampicillin

8

1

0.13

Terbinafine

2624

164

0.06

0.31

S

Cefotaxime

8

2

0.25

Terbinafine

2624

41

0.02

0.15

S

Azithromycin

1

0.125

0.13

Terbinafine

2624

41

0.02

0.15

S

Ciprofloxacin

2

0.25

0.13

Terbinafine

2624

82

0.03

0.16

S

Gentamycin

2

0.25

0.13

  1. FIC Fractional inhibitory concentration, FICI fractional inhibitory concentration index, S synergism